Open Access Policy Deposits
Parent: Department of Biological Chemistry, UCLA, David Geffen School of Medicine
eScholarship stats: Breakdown by Item for June through September, 2024
| Item | Title | Total requests | Download | View-only | %Dnld |
|---|---|---|---|---|---|
| 2ms7118k | Added Value of Internal Fragments for Top-Down Mass Spectrometry of Intact Monoclonal Antibodies and Antibody-Drug Conjugates. | 186 | 38 | 148 | 20.4% |
| 0gz1n6nw | Na,K-ATPase activity promotes macropinocytosis in colon cancer via Wnt signaling | 155 | 19 | 136 | 12.3% |
| 3bm6r902 | Cell Biology of the Mitochondrion | 153 | 16 | 137 | 10.5% |
| 7gn0w60g | A Novel Toxoplasma Inner Membrane Complex Suture-Associated Protein Regulates Suture Protein Targeting and Colocalizes with Membrane Trafficking Machinery | 150 | 29 | 121 | 19.3% |
| 9tv115kq | CysDB: a human cysteine database based on experimental quantitative chemoproteomics. | 145 | 23 | 122 | 15.9% |
| 1hj8z0df | Compositional Analysis of Complex Mixtures using Automatic MicroED Data Collection. | 143 | 23 | 120 | 16.1% |
| 44c6j6x9 | Molecular analysis of a self-organizing signaling pathway for Xenopus axial patterning from egg to tailbud | 138 | 30 | 108 | 21.7% |
| 7m02936s | Strategies to decrease inequalities in cancer therapeutics, care and prevention: Proceedings on a conference organized by the Pontifical Academy of Sciences and the European Academy of Cancer Sciences, Vatican City, February 23-24, 2023. | 138 | 21 | 117 | 15.2% |
| 0vx3z62x | SRA- and SET-domain-containing proteins link RNA polymerase V occupancy to DNA methylation | 135 | 38 | 97 | 28.1% |
| 9q16m5gm | The Pol II preinitiation complex (PIC) influences Mediator binding but not promoter–enhancer looping | 132 | 22 | 110 | 16.7% |
| 6h8689vt | The DGCR8 RNA-binding heme domain recognizes primary microRNAs by clamping the hairpin. | 128 | 30 | 98 | 23.4% |
| 162319w1 | Addition of exogenous diacylglycerol enhances Wnt/β-catenin signaling through stimulation of macropinocytosis. | 125 | 16 | 109 | 12.8% |
| 1kg6n08c | The metabolite α-ketoglutarate extends lifespan by inhibiting ATP synthase and TOR. | 121 | 17 | 104 | 14.0% |
| 2qz52657 | Transcriptional and epigenetic dysregulation impairs generation of proliferative neural stem and progenitor cells during brain aging. | 120 | 13 | 107 | 10.8% |
| 71b0j4nw | Polymorphic Structure Determination of the Macrocyclic Drug Paritaprevir by MicroED. | 119 | 21 | 98 | 17.6% |
| 0174853v | Expression Profiling of Attenuated Mitochondrial Function Identifies Retrograde Signals in Drosophila | 118 | 12 | 106 | 10.2% |
| 15g0r66f | “How Do We Do This at a Distance?!” A Descriptive Study of Remote Undergraduate Research Programs during COVID-19 | 117 | 31 | 86 | 26.5% |
| 9b10d0s8 | Cofilin-induced changes in F-actin detected via cross-linking with benzophenone-4-maleimide. | 117 | 17 | 100 | 14.5% |
| 3bh225tt | Identifying amyloid-related diseases by mapping mutations in low-complexity protein domains to pathologies | 113 | 30 | 83 | 26.5% |
| 6nv0q883 | De novo determination of mosquitocidal Cry11Aa and Cry11Ba structures from naturally-occurring nanocrystals | 113 | 32 | 81 | 28.3% |
| 69k286p7 | Eliminating the missing cone challenge through innovative approaches. | 111 | 21 | 90 | 18.9% |
| 90m132xc | Ultrafast Au(III)-Mediated Arylation of Cysteine | 110 | 0 | 110 | 0.0% |
| 2rw6m6jt | The DGCR8 RNA-Binding Heme Domain Recognizes Primary MicroRNAs by Clamping the Hairpin | 105 | 35 | 70 | 33.3% |
| 3tb646fs | Dawn and dusk peaks of outer segment phagocytosis, and visual cycle function require Rab28 | 105 | 33 | 72 | 31.4% |
| 8qm0p06g | RFECS: A Random-Forest Based Algorithm for Enhancer Identification from Chromatin State | 105 | 28 | 77 | 26.7% |
| 5qc137rx | Dichloroacetate should be considered with platinum-based chemotherapy in hypoxic tumors rather than as a single agent in advanced non-small cell lung cancer. | 103 | 11 | 92 | 10.7% |
| 1122r0tg | De novo designed protein inhibitors of amyloid aggregation and seeding | 99 | 23 | 76 | 23.2% |
| 9nh2d4t3 | The cardiomyocyte disrupts pyrimidine biosynthesis in non-myocytes to regulate heart repair | 99 | 17 | 82 | 17.2% |
| 78z3640x | Genome-wide analysis of dorsal and ventral transcriptomes of the Xenopus laevis gastrula | 98 | 26 | 72 | 26.5% |
| 2g22r9k6 | De novo determination of mosquitocidal Cry11Aa and Cry11Ba structures from naturally-occurring nanocrystals | 93 | 14 | 79 | 15.1% |
| 2gt2f135 | The CryoEM Method MicroED as a Powerful Tool for Small Molecule Structure Determination | 93 | 11 | 82 | 11.8% |
| 3vt8c06d | A pathogenic role for histone H3 copper reductase activity in a yeast model of Friedreich’s ataxia | 93 | 16 | 77 | 17.2% |
| 7xs3430q | Bruins-in-Genomics: Evaluation of the impact of a UCLA undergraduate summer program in computational biology on participating students. | 93 | 17 | 76 | 18.3% |
| 9bd8z0hh | Substrate twinning activates the signal recognition particle and its receptor | 93 | 15 | 78 | 16.1% |
| 1dc6s7xj | The GSK3 Signaling Axis Regulates Adaptive Glutamine Metabolism in Lung Squamous Cell Carcinoma. | 92 | 10 | 82 | 10.9% |
| 5p02n0xm | D-peptide-magnetic nanoparticles fragment tau fibrils and rescue behavioral deficits in a mouse model of Alzheimer’s disease | 92 | 34 | 58 | 37.0% |
| 03p035b0 | TFAP2C regulates transcription in human naive pluripotency by opening enhancers. | 88 | 5 | 83 | 5.7% |
| 2476r14p | A protein assembly mediates Xist localization and gene silencing | 88 | 7 | 81 | 8.0% |
| 6bv8c5kb | Functionalizing tandem mass tags for streamlining click-based quantitative chemoproteomics. | 86 | 33 | 53 | 38.4% |
| 3kz1p4b4 | RNA: The Unsuspected Conductor in the Orchestra of Macromolecular Crowding | 85 | 19 | 66 | 22.4% |
| 5nq3g3pw | Molecular basis for preventing α-synuclein aggregation by a molecular tweezer. | 85 | 15 | 70 | 17.6% |
| 61c3v6b7 | Interferon-mediated reprogramming of membrane cholesterol to evade bacterial toxins | 85 | 8 | 77 | 9.4% |
| 70b2315v | DNA methylation estimation using methylation-sensitive restriction enzyme bisulfite sequencing (MREBS) | 84 | 6 | 78 | 7.1% |
| 8619753x | In vivo targeting of de novo DNA methylation by histone modifications in yeast and mouse. | 84 | 9 | 75 | 10.7% |
| 3sz7m1tg | Introduction to the Thematic Minireview Series: Chromatin and transcription | 81 | 3 | 78 | 3.7% |
| 3t8708z1 | Single cell analysis reveals immune cell–adipocyte crosstalk regulating the transcription of thermogenic adipocytes | 81 | 16 | 65 | 19.8% |
| 5xs2g4st | AlphaFold-assisted structure determination of a bacterial protein of unknown function using X-ray and electron crystallography. | 81 | 31 | 50 | 38.3% |
| 4116h7ng | A mammalian methylation array for profiling methylation levels at conserved sequences | 80 | 2 | 78 | 2.5% |
| 04m512v0 | 4-(Nitrophenylsulfonyl)piperazines mitigate radiation damage to multiple tissues | 75 | 11 | 64 | 14.7% |
| 4nb2139c | Proximity-labeling chemoproteomics defines the subcellular cysteinome and inflammation-responsive mitochondrial redoxome | 74 | 1 | 73 | 1.4% |
Note: Due to the evolving nature of web traffic, the data presented here should be considered approximate and subject to revision. Learn more.