Open Access Policy Deposits

Parent: Department of Biological Chemistry, UCLA, David Geffen School of Medicine

eScholarship stats: Breakdown by Item for May through August, 2026

Item	Title	Total requests	Download	View-only	%Dnld
2rv6q3mh	Evo-Devo of Urbilateria and its larval forms	524	80	444	15.3%
4ph8w0v1	Genome-wide programmable transcriptional memory by CRISPR-based epigenome editing	518	75	443	14.5%
9wk3d379	Guidelines for the use and interpretation of assays for monitoring autophagy	484	251	233	51.9%
8fx6077v	Aster Proteins Facilitate Nonvesicular Plasma Membrane to ER Cholesterol Transport in Mammalian Cells	422	56	366	13.3%
8mx9d13m	CLSTN3β enforces adipocyte multilocularity to facilitate lipid utilization	401	332	69	82.8%
2z8359hb	p21+TREM2+ senescent macrophages fuel inflammaging and metabolic dysfunction-associated steatotic liver disease	391	260	131	66.5%
9nj3h75b	Top-down proteomics	378	271	107	71.7%
47j7d02f	Highlighting membrane protein structure and function: A celebration of the Protein Data Bank	370	294	76	79.5%
3kz1p4b4	RNA: The Unsuspected Conductor in the Orchestra of Macromolecular Crowding	358	239	119	66.8%
94x6112j	MOTS-c modulates skeletal muscle function by directly binding and activating CK2	358	134	224	37.4%
7fg0g9np	A Single-Cell Transcriptomic Atlas of Human Neocortical Development during Mid-gestation	348	241	107	69.3%
7tg783zh	Viral delivery of an RNA-guided genome editor for transgene-free germline editing in Arabidopsis	348	85	263	24.4%
5jw70238	Universal DNA methylation age across mammalian tissues	332	208	124	62.7%
9185g8gj	Histone H3 lysine 4 methylation recruits DNA demethylases to enforce gene expression in Arabidopsis	325	238	87	73.2%
9wc3z7zt	A multimodal cell census and atlas of the mammalian primary motor cortex	320	267	53	83.4%
20h7r6mq	Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets	319	122	197	38.2%
19q9d9bk	The PMA phorbol ester tumor promoter increases canonical Wnt signaling via macropinocytosis	310	162	148	52.3%
3mc5h238	Single-Cell Sequencing of Brain Cell Transcriptomes and Epigenomes	309	59	250	19.1%
3jt0c1rr	Drp1 regulates mitochondrial health and controls skeletal muscle mass through the Erk1/2-Nur77 pathway	302	101	201	33.4%
4b815887	Head organizer: Cerberus and IGF cooperate in brain induction in Xenopus embryos	300	174	126	58.0%
79x1b6h6	Comparative cellular analysis of motor cortex in human, marmoset and mouse	298	222	76	74.5%
1z72474s	BMP gradients: A paradigm for morphogen-mediated developmental patterning	288	124	164	43.1%
46k649vw	Mitochondria Bound to Lipid Droplets Have Unique Bioenergetics, Composition, and Dynamics that Support Lipid Droplet Expansion	288	50	238	17.4%
68v1446k	Photoaffinity labelling strategies for mapping the small molecule–protein interactome	279	150	129	53.8%
871433dz	Control of intestinal stem cell function and proliferation by mitochondrial pyruvate metabolism	268	43	225	16.0%
05t0m0s7	Island-specific evolution of a sex-primed autosome in a sexual planarian	260	183	77	70.4%
0wz709h3	Interaction of chikungunya virus glycoproteins with macrophage factors controls virion production	256	60	196	23.4%
7q45s22x	SE(3)-equivariant ternary complex prediction towards target protein degradation	255	89	166	34.9%
5ds8b5p6	Crosstalk between epitranscriptomic and epigenetic mechanisms in gene regulation	252	58	194	23.0%
4mx2r10v	An integrated encyclopedia of DNA elements in the human genome	251	88	163	35.1%
6t34b8sq	Reassessment of Exosome Composition	249	51	198	20.5%
1fp178nx	Allosteric Modulation of Pathological Ataxin-3 Aggregation: A Path to Spinocerebellar Ataxia Type-3 Therapies	246	89	157	36.2%
6dj2s3qr	A lifelong duty: how Xist maintains the inactive X chromosome	244	105	139	43.0%
4628w5w9	XIST directly regulates X-linked and autosomal genes in naive human pluripotent cells	243	64	179	26.3%
40k4w7jn	Defining STING–sterol interactions with chemoproteomics	239	92	147	38.5%
0pz7p754	Nuclear Localization of Mitochondrial TCA Cycle Enzymes as a Critical Step in Mammalian Zygotic Genome Activation	238	67	171	28.2%
1z03r1jd	A transcriptomic and epigenomic cell atlas of the mouse primary motor cortex	236	146	90	61.9%
2tm2k9gd	Neural basis of prosocial behavior	236	63	173	26.7%
6rf7545c	Estrogen receptor α controls metabolism in white and brown adipocytes by regulating Polg1 and mitochondrial remodeling	234	137	97	58.5%
7s9850mt	N-Myristoytransferase Inhibition Causes Mitochondrial Iron Overload and Parthanatos in TIM17A-Dependent Aggressive Lung Carcinoma	233	92	141	39.5%
1984850q	STEM: a tool for the analysis of short time series gene expression data	232	29	203	12.5%
36v4s1vn	A synthetic coolant (WS-23) in disposable electronic cigarettes impairs cytoskeletal function in EpiAirway microtissues exposed at the air liquid interface	230	132	98	57.4%
0nj3p8sn	Cell Biology of Canonical Wnt Signaling	228	127	101	55.7%
2wh7165f	The Histone Variant H2A.W Defines Heterochromatin and Promotes Chromatin Condensation in Arabidopsis	225	23	202	10.2%
1q76t50g	Lactate dehydrogenase activity drives hair follicle stem cell activation	220	44	176	20.0%
3ww660hs	Skeletal muscle action of estrogen receptor α is critical for the maintenance of mitochondrial function and metabolic homeostasis in females	220	82	138	37.3%
1cx8v95f	Hepatic nonvesicular cholesterol transport is critical for systemic lipid homeostasis	218	79	139	36.2%
8hx7x3g9	Wnt, GSK3, and Macropinocytosis	218	109	109	50.0%
1hw2599f	The histone H3 variant H3.3 regulates gene body DNA methylation in Arabidopsis thaliana	217	0	217	0.0%
83s4x4vm	Protocol for organelle-specific cysteine capture and quantification of cysteine oxidation state	216	87	129	40.3%

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