Open Access Policy Deposits

Parent: Department of Biological Chemistry, UCLA, David Geffen School of Medicine

eScholarship stats: Breakdown by Item for March through June, 2025

ItemTitleTotal requestsDownloadView-only%Dnld
3bm6r902Cell Biology of the Mitochondrion17261663.5%
4h4495x5Ectopic targeting of CG DNA methylation in Arabidopsis with the bacterial SssI methyltransferase159101496.3%
0nj3p8snCell Biology of Canonical Wnt Signaling1532812518.3%
1q76t50gLactate dehydrogenase activity drives hair follicle stem cell activation148141349.5%
9q72d0dkCRISPR-based targeting of DNA methylation in Arabidopsis thaliana by a bacterial CG-specific DNA methyltransferase142101327.0%
8cs8z9p3Improving the solubility of pseudo-hydrophobic chemicals through co-crystal formulation.13431312.2%
68v1446kPhotoaffinity labelling strategies for mapping the small molecule–protein interactome130389229.2%
9185g8gjHistone H3 lysine 4 methylation recruits DNA demethylases to enforce gene expression in Arabidopsis.130597145.4%
0fh0h194Double assurance in the induction of axial development by egg dorsal determinants in Xenopus embryos129408931.0%
4q99m9rwAccurate design of co-assembling multi-component protein nanomaterials128497938.3%
0w64157xInternal Fragments Enhance Middle-Down Mass Spectrometry Structural Characterization of Monoclonal Antibodies and Antibody-Drug Conjugates.1231610713.0%
59b2218pDesign of ordered two-dimensional arrays mediated by noncovalent protein-protein interfaces114268822.8%
9nh2d4t3The cardiomyocyte disrupts pyrimidine biosynthesis in non-myocytes to regulate heart repair114111039.6%
06k5w7g0Structure of the lens MP20 mediated adhesive junction.112159713.4%
77t5d3q4ABL fusion oncogene transformation and inhibitor sensitivity are mediated by the cellular regulator RIN1.10861025.6%
4ph8w0v1Genome-wide programmable transcriptional memory by CRISPR-based epigenome editing107476043.9%
3g79735qMicroED Structures of Fluticasone Furoate and Fluticasone Propionate Provide New Insights into Their Function.1068987.5%
5vg8s806Systematic discovery of conservation states for single-nucleotide annotation of the human genome.1047976.7%
2mc7j5vsTandem metabolic reaction-based sensors unlock in vivo metabolomics.103129111.7%
56j017g9Single nucleus multi-omics identifies human cortical cell regulatory genome diversity101326931.7%
6274g8m7Damaging mutations in liver X receptor-α are hepatotoxic and implicate cholesterol sensing in liver health1017946.9%
05p11699Uncovering the Elusive Structures and Mechanisms of Prevalent Antidepressants.1007937.0%
8xm482tkEngineering an allosteric transcription factor to respond to new ligands.100544654.0%
5272f4bcA functional genomics screen identifying blood cell development genes in Drosophila by undergraduates participating in a course-based research experience99138613.1%
70b2315vDNA methylation estimation using methylation-sensitive restriction enzyme bisulfite sequencing (MREBS)996936.1%
6qp7s3ccAsparagine promotes cancer cell proliferation through use as an amino acid exchange factor978898.2%
064987qhRecovering high-resolution information using energy filtering in MicroED.95138213.7%
6vq1b3psSpatial profiling of the interplay between cell type- and vision-dependent transcriptomic programs in the visual cortex95108510.5%
8f18t8wnAtomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED.95504552.6%
9bd8z0hhSubstrate twinning activates the signal recognition particle and its receptor95128312.6%
6cn1q64tDefects in the Medial Entorhinal Cortex and Dentate Gyrus in the Mouse Model of Sanfilippo Syndrome Type B942922.1%
6nv0q883De novo determination of mosquitocidal Cry11Aa and Cry11Ba structures from naturally-occurring nanocrystals93118211.8%
8mx9d13mCLSTN3β enforces adipocyte multilocularity to facilitate lipid utilization93326134.4%
08d3p8vkAsparagine couples mitochondrial respiration to ATF4 activity and tumor growth92118112.0%
54g7c1bpCortical regulation of helping behaviour towards others in pain.92246826.1%
5pr5k9vrEnergy filtering enables macromolecular MicroED data at sub-atomic resolution.92147815.2%
1z72474sBMP gradients: A paradigm for morphogen-mediated developmental patterning91325935.2%
38v8j6fzA high-resolution map of human evolutionary constraint using 29 mammals91236825.3%
78z3640xGenome-wide analysis of dorsal and ventral transcriptomes of the Xenopus laevis gastrula915865.5%
5v00z3sfAtlas of fetal metabolism during mid-to-late gestation and diabetic pregnancy.90226824.4%
62j4r8dnStructure of a designed tetrahedral protein assembly variant engineered to have improved soluble expression908828.9%
7s9850mtN-Myristoytransferase Inhibition Causes Mitochondrial Iron Overload and Parthanatos in TIM17A-Dependent Aggressive Lung Carcinoma90365440.0%
82q3d98qVision-dependent specification of cell types and function in the developing cortex90375341.1%
8619753xIn vivo targeting of de novo DNA methylation by histone modifications in yeast and mouse.902882.2%
2b27t47jStructural Characterization of a Thrombin-Aptamer Complex by High Resolution Native Top-Down Mass Spectrometry89503956.2%
3t8708z1Single cell analysis reveals immune cell–adipocyte crosstalk regulating the transcription of thermogenic adipocytes898819.0%
9nf8q0shHistone H3 cysteine 110 enhances iron metabolism and modulates replicative life span in Saccharomyces cerevisiae.89127713.5%
9nj3h75bTop-down proteomics.89236625.8%
07r1j11rInsight into the autoproteolysis mechanism of the RsgI9 anti-σ factor from Clostridium thermocellum.88375142.0%
35s312ffAn activation-based high throughput screen identifies caspase-10 inhibitors88157317.0%

Note: Due to the evolving nature of web traffic, the data presented here should be considered approximate and subject to revision. Learn more.