Biomedical Sciences Open Access Policy Deposits

eScholarship stats: Breakdown by Item for July through October, 2026

Item	Title	Total requests	Download	View-only	%Dnld
80m7x5x5	Diet high in linoleic acid dysregulates the intestinal endocannabinoid system and increases susceptibility to colitis in Mice	732	86	646	11.7%
99h2f9m1	Neuroinflammation in Alzheimer's disease	640	365	275	57.0%
1hg0j39v	Adolescent exposure to low-dose THC disrupts energy balance and adipose organ homeostasis in adulthood	611	526	85	86.1%
6x66v4k6	Sperm tsRNAs contribute to intergenerational inheritance of an acquired metabolic disorder	562	193	369	34.3%
87f229pf	PANDORA-seq expands the repertoire of regulatory small RNAs by overcoming RNA modifications	391	190	201	48.6%
7xh0f542	Expression of the Astrocyte Water Channel Aquaporin-4 in the Mouse Brain	349	38	311	10.9%
3v81t4m7	Comprehensive Characterization of Cancer Driver Genes and Mutations	325	142	183	43.7%
6g2402qg	Omega-3 Fatty Acid Intake by Age, Gender, and Pregnancy Status in the United States: National Health and Nutrition Examination Survey 2003–2014	285	252	33	88.4%
0z5275h1	Superstable lipid vacuoles endow cartilage with its shape and biomechanics	281	147	134	52.3%
0th8v0p9	Transparent nanocrystalline yttria-stabilized-zirconia calvarium prosthesis	268	61	207	22.8%
6mt9t3pk	T cell protein tyrosine phosphatase protects intestinal barrier function by restricting epithelial tight junction remodeling	252	150	102	59.5%
7924f58g	Chronic, Low-Dose Methamphetamine Reveals Sexual Dimorphism of Memory Performance, Histopathology, and Gene Expression Affected by HIV-1 Tat Protein in a Transgenic Model of NeuroHIV	240	198	42	82.5%
7133w77s	Anhedonia Following Early-Life Adversity Involves Aberrant Interaction of Reward and Anxiety Circuits and Is Reversed by Partial Silencing of Amygdala Corticotropin-Releasing Hormone Gene	232	70	162	30.2%
6fg322fk	PTBP1 depletion in mature astrocytes reveals distinct splicing alterations without neuronal features	231	147	84	63.6%
5792d8d1	Rapid, sensitive, and species-independent detection of Crimean Congo hemorrhagic fever virus nucleoprotein and GP38 antibodies	227	161	66	70.9%
2154f71k	Dynamic changes in human single-cell transcriptional signatures during fatal sepsis	219	149	70	68.0%
7hz2m2b3	Hypoxia and Inflammation: Insights From High-Altitude Physiology	215	56	159	26.0%
6kq1b2jp	Consistent induction of chronic experimental autoimmune encephalomyelitis in C57BL/6 mice for the longitudinal study of pathology and repair	211	79	132	37.4%
9fs9w67h	Neuroendocrinology and the Genetics of Obesity	206	106	100	51.5%
2dk563d8	The structure of Haemophilus influenzae prephenate dehydrogenase suggests unique features of bifunctional TyrA enzymes	204	32	172	15.7%
9742k8ch	Epistatic interactions between NMD and TRP53 control progenitor cell maintenance and brain size	204	136	68	66.7%
5cj0z7jv	Specification and formation of the neural crest: Perspectives on lineage segregation	197	39	158	19.8%
9p0089pv	Mechanisms of Intestinal Epithelial Barrier Dysfunction by Adherent-Invasive Escherichia coli	197	55	142	27.9%
08x970sr	Mass Spectrometry-Based Direct Sequencing of tRNAs De Novo and Quantitative Mapping of Multiple RNA Modifications	196	68	128	34.7%
301566ks	Increased body weight in mice with fragile X messenger ribonucleoprotein 1 (Fmr1) gene mutation is associated with hypothalamic dysfunction	195	54	141	27.7%
4mp8t99k	iPSC-Derived Human Microglia-like Cells to Study Neurological Diseases	195	41	154	21.0%
7f62z674	A delicate balance: role of MMP-9 in brain development and pathophysiology of neurodevelopmental disorders	192	75	117	39.1%
3r1357xw	The SARS-CoV‑2 SSHHPS Recognized by the Papain-like Protease	191	147	44	77.0%
8n2703bv	Choline metabolism underpins macrophage IL-4 polarization and RELMα up-regulation in helminth infection	188	50	138	26.6%
06m8h7sm	Cholinergic Neurotransmission Controls Orexigenic Endocannabinoid Signaling in the Gut in Diet-Induced Obesity.	187	136	51	72.7%
8xg946qf	Decoding the origins of cellular self-organization for engineered biology	187	108	79	57.8%
6j39d1ck	Dnmt2 mediates intergenerational transmission of paternally acquired metabolic disorders through sperm small non-coding RNAs	186	79	107	42.5%
5j98r7hw	Structure- and context-based analysis of the GxGYxYP family reveals a new putative class of Glycoside Hydrolase	179	41	138	22.9%
3045j306	PDBFlex: exploring flexibility in protein structures	178	29	149	16.3%
00g0z278	tRNA renovatio: Rebirth through fragmentation	175	102	73	58.3%
9vn885p1	The lysosomal GPCR-like protein GPR137B regulates Rag and mTORC1 localization and activity	175	89	86	50.9%
9842k2nh	Origins and evolving functionalities of tRNA-derived small RNAs	173	55	118	31.8%
19n4r9tt	Time Domains of Hypoxia Responses and -Omics Insights	171	48	123	28.1%
60z9w6jc	Oxidative Stress Activates Endothelial Innate Immunity via Sterol Regulatory Element Binding Protein 2 (SREBP2) Transactivation of MicroRNA-92a	169	33	136	19.5%
0nw2196m	Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen	168	78	90	46.4%
3100h0cm	Asymmetric Expression of LincGET Biases Cell Fate in Two-Cell Mouse Embryos	167	138	29	82.6%
5gp1036g	Genetic variants at the EGLN1 locus associated with high‐altitude adaptation in Tibetans are absent or found at low frequency in highland Andeans	165	51	114	30.9%
05s7d1tb	Here, there and everywhere: Resistin-like molecules in infection, inflammation, and metabolic disorders	156	49	107	31.4%
1056c8gq	Harnessing preexisting influenza virus-specific immunity increases antibody responses against SARS-CoV-2	155	48	107	31.0%
4x6590cz	PTPN2 Is a Critical Regulator of Ileal Paneth Cell Viability and Function in Mice	155	111	44	71.6%
019146q9	Identification and phylogenetic analysis of RNA binding domain abundant in apicomplexans or RAP proteins	154	120	34	77.9%
07r9t5j5	The drying Salton Sea and asthma: A perspective on a “natural” disaster	154	67	87	43.5%
8qd430n4	EphB2 Signaling Is Implicated in Astrocyte-Mediated Parvalbumin Inhibitory Synapse Development	154	132	22	85.7%
1vc5t3gv	Diet-Induced Obesity Elicits Macrophage Infiltration and Reduction in Spine Density in the Hypothalami of Male but Not Female Mice	153	25	128	16.3%
9rx4r1cb	A cholesterol-responsive hepatic tRNA-derived small RNA regulates cholesterol homeostasis and atherosclerosis development	153	47	106	30.7%

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Note: Due to the evolving nature of web traffic, the data presented here should be considered approximate and subject to revision. Learn more.