Biomedical Sciences Open Access Policy Deposits

eScholarship stats: History by Item for July through October, 2026

Item	Title	Total requests	2026-10	2026-09	2026-08	2026-07
80m7x5x5	Diet high in linoleic acid dysregulates the intestinal endocannabinoid system and increases susceptibility to colitis in Mice	732	75	257	339	61
99h2f9m1	Neuroinflammation in Alzheimer's disease	640	215	136	138	151
1hg0j39v	Adolescent exposure to low-dose THC disrupts energy balance and adipose organ homeostasis in adulthood	611	157	249	170	35
6x66v4k6	Sperm tsRNAs contribute to intergenerational inheritance of an acquired metabolic disorder	562	145	116	172	129
87f229pf	PANDORA-seq expands the repertoire of regulatory small RNAs by overcoming RNA modifications	391	110	92	117	72
7xh0f542	Expression of the Astrocyte Water Channel Aquaporin-4 in the Mouse Brain	349	57	64	104	124
3v81t4m7	Comprehensive Characterization of Cancer Driver Genes and Mutations	325	96	75	75	79
6g2402qg	Omega-3 Fatty Acid Intake by Age, Gender, and Pregnancy Status in the United States: National Health and Nutrition Examination Survey 2003–2014	285	29	99	115	42
0z5275h1	Superstable lipid vacuoles endow cartilage with its shape and biomechanics	281	94	70	53	64
0th8v0p9	Transparent nanocrystalline yttria-stabilized-zirconia calvarium prosthesis	268	128	58	54	28
6mt9t3pk	T cell protein tyrosine phosphatase protects intestinal barrier function by restricting epithelial tight junction remodeling	252	68	59	79	46
7924f58g	Chronic, Low-Dose Methamphetamine Reveals Sexual Dimorphism of Memory Performance, Histopathology, and Gene Expression Affected by HIV-1 Tat Protein in a Transgenic Model of NeuroHIV	240	63	71	49	57
7133w77s	Anhedonia Following Early-Life Adversity Involves Aberrant Interaction of Reward and Anxiety Circuits and Is Reversed by Partial Silencing of Amygdala Corticotropin-Releasing Hormone Gene	232	59	67	54	52
6fg322fk	PTBP1 depletion in mature astrocytes reveals distinct splicing alterations without neuronal features	231	82	56	49	44
5792d8d1	Rapid, sensitive, and species-independent detection of Crimean Congo hemorrhagic fever virus nucleoprotein and GP38 antibodies	227	50	54	56	67
2154f71k	Dynamic changes in human single-cell transcriptional signatures during fatal sepsis	219	60	69	60	30
7hz2m2b3	Hypoxia and Inflammation: Insights From High-Altitude Physiology	215	48	72	67	28
6kq1b2jp	Consistent induction of chronic experimental autoimmune encephalomyelitis in C57BL/6 mice for the longitudinal study of pathology and repair	211	79	53	43	36
9fs9w67h	Neuroendocrinology and the Genetics of Obesity	206	45	78	56	27
2dk563d8	The structure of Haemophilus influenzae prephenate dehydrogenase suggests unique features of bifunctional TyrA enzymes	204	29	77	31	67
9742k8ch	Epistatic interactions between NMD and TRP53 control progenitor cell maintenance and brain size	204	56	30	56	62
5cj0z7jv	Specification and formation of the neural crest: Perspectives on lineage segregation	197	42	25	103	27
9p0089pv	Mechanisms of Intestinal Epithelial Barrier Dysfunction by Adherent-Invasive Escherichia coli	197	37	109	23	28
08x970sr	Mass Spectrometry-Based Direct Sequencing of tRNAs De Novo and Quantitative Mapping of Multiple RNA Modifications	196	53	102	25	16
301566ks	Increased body weight in mice with fragile X messenger ribonucleoprotein 1 (Fmr1) gene mutation is associated with hypothalamic dysfunction	195	41	105	26	23
4mp8t99k	iPSC-Derived Human Microglia-like Cells to Study Neurological Diseases	195	81	49	38	27
7f62z674	A delicate balance: role of MMP-9 in brain development and pathophysiology of neurodevelopmental disorders	192	39	80	44	29
3r1357xw	The SARS-CoV‑2 SSHHPS Recognized by the Papain-like Protease	191	73	31	41	46
8n2703bv	Choline metabolism underpins macrophage IL-4 polarization and RELMα up-regulation in helminth infection	188	100	29	53	6
06m8h7sm	Cholinergic Neurotransmission Controls Orexigenic Endocannabinoid Signaling in the Gut in Diet-Induced Obesity.	187	32	38	44	73
8xg946qf	Decoding the origins of cellular self-organization for engineered biology	187	46	49	39	53
6j39d1ck	Dnmt2 mediates intergenerational transmission of paternally acquired metabolic disorders through sperm small non-coding RNAs	186	57	74	30	25
5j98r7hw	Structure- and context-based analysis of the GxGYxYP family reveals a new putative class of Glycoside Hydrolase	179	68	54	34	23
3045j306	PDBFlex: exploring flexibility in protein structures	178	30	24	107	17
00g0z278	tRNA renovatio: Rebirth through fragmentation	175	54	50	42	29
9vn885p1	The lysosomal GPCR-like protein GPR137B regulates Rag and mTORC1 localization and activity	175	52	63	34	26
9842k2nh	Origins and evolving functionalities of tRNA-derived small RNAs	173	52	49	44	28
19n4r9tt	Time Domains of Hypoxia Responses and -Omics Insights	171	49	42	44	36
60z9w6jc	Oxidative Stress Activates Endothelial Innate Immunity via Sterol Regulatory Element Binding Protein 2 (SREBP2) Transactivation of MicroRNA-92a	169	50	48	55	16
0nw2196m	Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen	168	51	62	39	16
3100h0cm	Asymmetric Expression of LincGET Biases Cell Fate in Two-Cell Mouse Embryos	167	43	30	57	37
5gp1036g	Genetic variants at the EGLN1 locus associated with high‐altitude adaptation in Tibetans are absent or found at low frequency in highland Andeans	165	61	33	54	17
05s7d1tb	Here, there and everywhere: Resistin-like molecules in infection, inflammation, and metabolic disorders	156	48	44	47	17
1056c8gq	Harnessing preexisting influenza virus-specific immunity increases antibody responses against SARS-CoV-2	155	63	29	27	36
4x6590cz	PTPN2 Is a Critical Regulator of Ileal Paneth Cell Viability and Function in Mice	155	64	32	29	30
019146q9	Identification and phylogenetic analysis of RNA binding domain abundant in apicomplexans or RAP proteins	154	39	31	37	47
07r9t5j5	The drying Salton Sea and asthma: A perspective on a “natural” disaster	154	63	30	35	26
8qd430n4	EphB2 Signaling Is Implicated in Astrocyte-Mediated Parvalbumin Inhibitory Synapse Development	154	51	30	33	40
1vc5t3gv	Diet-Induced Obesity Elicits Macrophage Infiltration and Reduction in Spine Density in the Hypothalami of Male but Not Female Mice	153	19	102	18	14
9rx4r1cb	A cholesterol-responsive hepatic tRNA-derived small RNA regulates cholesterol homeostasis and atherosclerosis development	153	60	28	43	22

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