Open Access Policy Deposits

eScholarship stats: Breakdown by Item for July through October, 2026

Item	Title	Total requests	Download	View-only	%Dnld
80m7x5x5	Diet high in linoleic acid dysregulates the intestinal endocannabinoid system and increases susceptibility to colitis in Mice	732	86	646	11.7%
1hg0j39v	Adolescent exposure to low-dose THC disrupts energy balance and adipose organ homeostasis in adulthood	611	526	85	86.1%
7xh0f542	Expression of the Astrocyte Water Channel Aquaporin-4 in the Mouse Brain	349	38	311	10.9%
0th8v0p9	Transparent nanocrystalline yttria-stabilized-zirconia calvarium prosthesis	268	61	207	22.8%
6mt9t3pk	T cell protein tyrosine phosphatase protects intestinal barrier function by restricting epithelial tight junction remodeling	252	150	102	59.5%
4cb5z6xn	Pathways to opioid use and implications for prevention: voices of young adults in recovery	243	65	178	26.7%
7924f58g	Chronic, Low-Dose Methamphetamine Reveals Sexual Dimorphism of Memory Performance, Histopathology, and Gene Expression Affected by HIV-1 Tat Protein in a Transgenic Model of NeuroHIV	240	198	42	82.5%
5792d8d1	Rapid, sensitive, and species-independent detection of Crimean Congo hemorrhagic fever virus nucleoprotein and GP38 antibodies	227	161	66	70.9%
0jh1v95b	Phylogenetic analysis of mammalian maximal oxygen consumption during exercise	225	98	127	43.6%
2154f71k	Dynamic changes in human single-cell transcriptional signatures during fatal sepsis	219	149	70	68.0%
1xq2h3nb	Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention	217	110	107	50.7%
2qc5p3hp	Revisiting a Key Innovation in Evolutionary Biology: Felsenstein's "Phylogenies and the Comparative Method".	210	97	113	46.2%
9p0089pv	Mechanisms of Intestinal Epithelial Barrier Dysfunction by Adherent-Invasive Escherichia coli	197	55	142	27.9%
3r1357xw	The SARS-CoV‑2 SSHHPS Recognized by the Papain-like Protease	191	147	44	77.0%
8n2703bv	Choline metabolism underpins macrophage IL-4 polarization and RELMα up-regulation in helminth infection	188	50	138	26.6%
06m8h7sm	Cholinergic Neurotransmission Controls Orexigenic Endocannabinoid Signaling in the Gut in Diet-Induced Obesity.	187	136	51	72.7%
3cd1w8x3	Hormones and the Evolution of Complex Traits: Insights from Artificial Selection on Behavior	179	21	158	11.7%
53q3t4n0	Can a Hybrid Line Break a Selection Limit on Behavioral Evolution in Mice?	171	48	123	28.1%
52k1w89f	Locomotor kinematics on sand vs. vinyl flooring in the sidewinder rattlesnake Crotalus cerastes	165	89	76	53.9%
9vs2j9z6	Alcohol Use Disorder Risk and Protective Factors and Associated Harms Among Pacific Islander Young Adults	160	11	149	6.9%
05s7d1tb	Here, there and everywhere: Resistin-like molecules in infection, inflammation, and metabolic disorders	156	49	107	31.4%
4x6590cz	PTPN2 Is a Critical Regulator of Ileal Paneth Cell Viability and Function in Mice	155	111	44	71.6%
627342x0	Sex Work, Heroin Injection, and HIV Risk in Tijuana: A Love Story	154	22	132	14.3%
8qd430n4	EphB2 Signaling Is Implicated in Astrocyte-Mediated Parvalbumin Inhibitory Synapse Development	154	132	22	85.7%
1vc5t3gv	Diet-Induced Obesity Elicits Macrophage Infiltration and Reduction in Spine Density in the Hypothalami of Male but Not Female Mice	153	25	128	16.3%
20h6k5qk	Structural characterization of protective non-neutralizing antibodies targeting Crimean-Congo hemorrhagic fever virus	151	43	108	28.5%
0j99596k	Universal metabolic constraints shape the evolutionary ecology of diving in animals	147	42	105	28.6%
0nr9q1w8	Exploring Space‐Time Interactions in Fatal Opioid Overdoses	145	109	36	75.2%
3g044870	PTPN2 Regulates Interactions Between Macrophages and Intestinal Epithelial Cells to Promote Intestinal Barrier Function	144	48	96	33.3%
50t384rp	Hydrogen peroxide scavenger, catalase, alleviates ion transport dysfunction in murine colitis	143	34	109	23.8%
0tt0x846	Mechanisms underlying HIV-associated cognitive impairment and emerging therapies for its management	139	91	48	65.5%
86v0d479	Developmental exposure to indoor flame retardants and hypothalamic molecular signatures: Sex-dependent reprogramming of lipid homeostasis	138	108	30	78.3%
1ff7g8vn	Crimean Congo hemorrhagic fever virus nucleoprotein and GP38 subunit vaccine combination prevents morbidity in mice	134	75	59	56.0%
836694fh	Sex Differences in Opioid and Psychostimulant Craving and Relapse: A Critical Review	130	91	39	70.0%
6d45h9cp	Still little evidence sex differences in spatial navigation are evolutionary adaptations	125	40	85	32.0%
6887n486	A critical role for Macrophage-derived Cysteinyl-Leukotrienes in HIV-1 induced neuronal injury	119	0	119	0.0%
0zw5r5sk	Methamphetamine and Cannabis: A Tale of Two Drugs and their Effects on HIV, Brain, and Behavior	116	43	73	37.1%
4581t0pv	Interferon-β deficiency alters brain response to chronic HIV-1 envelope protein exposure in a transgenic model of NeuroHIV	115	41	74	35.7%
89b0m0gm	Macrophage-Regulatory T Cell Interactions Promote Type 2 Immune Homeostasis Through Resistin-Like Molecule α	114	61	53	53.5%
4128p7gr	“Violence and love and drugs…it all goes hand in hand”: A mixed methods analysis of the substance abuse, violence, and HIV/AIDS syndemic among women who use methamphetamine	113	67	46	59.3%
5cq5p3n0	IBD Candidate Genes and Intestinal Barrier Regulation	111	45	66	40.5%
2nm031x7	Endocannabinoids and the Gut-Brain Control of Food Intake and Obesity	109	29	80	26.6%
42d2w33x	Reclusive chandeliers: Functional isolation of dentate axo-axonic cells after experimental status epilepticus	108	34	74	31.5%
2fg5t266	Evidence of injection drug use in Kisumu, Kenya: Implications for HIV prevention	107	31	76	29.0%
5wp3q2w5	High Ca2+ Influx During Traumatic Brain Injury Leads to Caspase-1-Dependent Neuroinflammation and Cell Death	107	18	89	16.8%
0g44s46q	CX3CR1‐Expressing Myeloid Cells Regulate Host–Helminth Interaction and Lung Inflammation	106	71	35	67.0%
1p66j4tw	Biological/Genetic Regulation of Physical Activity Level	106	26	80	24.5%
70s1d9tq	Maternal exposure to Western diet affects adult body composition and voluntary wheel running in a genotype-specific manner in mice	106	20	86	18.9%
0n74242r	Targeting Mitochondrial Proline Dehydrogenase with a Suicide Inhibitor to Exploit Synthetic Lethal Interactions with p53 Upregulation and Glutaminase Inhibition	105	30	75	28.6%
32f4h2qt	Are Waterpipe Café, Vape Shop, and Traditional Tobacco Retailer Locations Associated with Community Composition and Young Adult Tobacco Use in North Carolina and Virginia?	105	27	78	25.7%

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Note: Due to the evolving nature of web traffic, the data presented here should be considered approximate and subject to revision. Learn more.