UC Riverside

ABSTRACT This study investigates fatal opioid overdoses in Riverside County, California, between January 2020 and March 2023, employing advanced spatial‐temporal analysis methods to uncover significant clusters and their underlying contexts. By integrating global and local Knox tests, the research identifies both broad trends and specific hotspots of fatal overdoses. The findings reveal substantial spatial disparities, with higher overdose rates in rural areas and neighborhoods characterized by lower socioeconomic status and larger Hispanic populations. Despite a lower overall overdose risk among Hispanics, their neighborhoods exhibit a higher occurrence of fatal overdoses, highlighting complex interactions between individual and environmental factors. These insights underscore the need for targeted, contextually informed public health interventions and policies to effectively address the opioid crisis.