Department of Cellular & Molecular Medicine - Open Access Policy Deposits

eScholarship stats: History by Item for March through June, 2026

Item	Title	Total requests	2026-06	2026-05	2026-04	2026-03
7rs018c6	Gain-of-function cardiomyopathic mutations in RBM20 rewire splicing regulation and re-distribute ribonucleoprotein granules within processing bodies	774	50	639	48	37
9wk3d379	Guidelines for the use and interpretation of assays for monitoring autophagy	622	117	128	184	193
9044v022	Brain organoids, consciousness, ethics and moral status	556	99	193	119	145
172879gx	Age-Dependent Brain Gene Expression and Copy Number Anomalies in Autism Suggest Distinct Pathological Processes at Young Versus Mature Ages	531	31	426	46	28
0jb936p7	Mechanism of STMN2 cryptic splice-polyadenylation and its correction for TDP-43 proteinopathies	470	120	150	106	94
551458jj	APOE4/4 is linked to damaging lipid droplets in Alzheimer’s disease microglia	469	175	119	81	94
3pv76061	E-cigarettes compromise the gut barrier and trigger inflammation	419	92	93	117	117
5s47j042	First Organoid Intelligence (OI) workshop to form an OI community	410	74	128	105	103
0914g67c	A comparative atlas of single-cell chromatin accessibility in the human brain	395	86	83	98	128
00g3j9wp	Cryptic splicing of stathmin-2 and UNC13A mRNAs is a pathological hallmark of TDP-43-associated Alzheimer’s disease	392	99	129	100	64
70c3m48j	Spindle assembly checkpoint activation and silencing at kinetochores	377	78	116	91	92
28k88901	Transcription Factor 4 loss-of-function is associated with deficits in progenitor proliferation and cortical neuron content	366	75	111	87	93
3cv2t1d1	Mechanism and reconstitution of circadian transcription in cyanobacteria	356	77	115	80	84
4bd0d5ws	An environment-dependent transcriptional network specifies human microglia identity	346	102	81	88	75
2nz1949j	A large-scale binding and functional map of human RNA-binding proteins	343	99	117	83	44
0r30n2q3	Adipose tissue macrophages secrete small extracellular vesicles that mediate rosiglitazone-induced insulin sensitization	339	100	123	80	36
1jm982xv	Decoding ALS: from genes to mechanism	339	105	83	86	65
10h0243m	Sequential membrane- and protein-bound organelles compartmentalize genomes during phage infection	332	98	92	71	71
8fz9q8fw	Lipid-associated macrophages’ promotion of fibrosis resolution during MASH regression requires TREM2	329	79	81	95	74
2pp4w8dz	The complexity of tobacco smoke-induced mutagenesis in head and neck cancer	327	74	97	97	59
3mk2678t	Exploring the consequences of redirecting an exocytic Rab onto endocytic vesicles	318	73	83	81	81
2bq0m1f2	Reduced signal for polygenic adaptation of height in UK Biobank	298	82	99	77	40
68k9w7dj	A living organoid biobank of patients with Crohn’s disease reveals molecular subtypes for personalized therapeutics	291	65	83	82	61
1m706149	Reversing a model of Parkinson’s disease with in situ converted nigral neurons	288	77	97	75	39
4vt1n111	A phage nucleus-associated RNA-binding protein is required for jumbo phage infection	284	77	85	70	52
4ch9n51h	Mitotic tethering enables inheritance of shattered micronuclear chromosomes	280	88	99	56	37
0503r9x1	Adult stem cell-derived complete lung organoid models emulate lung disease in COVID-19	275	65	81	85	44
7m89k316	Nuclear miR-320 Mediates Diabetes-Induced Cardiac Dysfunction by Activating Transcription of Fatty Acid Metabolic Genes to Cause Lipotoxicity in the Heart	274	125	54	63	32
0063305k	Sequential regulatory loops as key gatekeepers for neuronal reprogramming in human cells	270	70	84	59	57
16h8932r	Multiomic QTL mapping reveals phenotypic complexity of GWAS loci and prioritizes putative causal variants	268	61	73	75	59
6nt244k4	Generation of ‘semi-guided’ cortical organoids with complex neural oscillations	267	57	74	56	80
9jp3g347	The SARS-CoV-2 nucleocapsid phosphoprotein forms mutually exclusive condensates with RNA and the membrane-associated M protein	262	57	108	61	36
01j548f4	Perspectives on ENCODE	260	52	86	70	52
0bw638xs	Architecture and self-assembly of the jumbo bacteriophage nuclear shell	260	70	66	75	49
8vw4s1s8	Robust transcriptome-wide discovery of RNA-binding protein binding sites with enhanced CLIP (eCLIP)	257	39	76	83	59
60k166zd	The sustained expression of Cas9 targeting toxic RNAs reverses disease phenotypes in mouse models of myotonic dystrophy type 1	251	35	51	74	91
0tt0x846	Mechanisms underlying HIV-associated cognitive impairment and emerging therapies for its management	248	48	87	68	45
1k65z54f	Microbiome–microglia connections via the gut–brain axis	248	93	80	43	32
2gr9g49c	Liver-Derived Signals Sequentially Reprogram Myeloid Enhancers to Initiate and Maintain Kupffer Cell Identity	243	55	61	74	53
6z9096mf	An in vivo neuroimmune organoid model to study human microglia phenotypes	242	55	69	62	56
8670n4cq	Three-dimensional bioprinted glioblastoma microenvironments model cellular dependencies and immune interactions	240	63	62	63	52
0xm8q84f	Circular ecDNA promotes accessible chromatin and high oncogene expression	237	59	51	65	62
3pd6q5r4	Promoter-proximal CTCF binding promotes distal enhancer-dependent gene activation	237	71	67	57	42
8bg9p9r4	Messenger RNA Oxidation Occurs Early in Disease Pathogenesis and Promotes Motor Neuron Degeneration in ALS	237	55	87	50	45
9093x51q	Complex Oscillatory Waves Emerging from Cortical Organoids Model Early Human Brain Network Development	237	53	64	62	58
27v4m3md	Role of H3K4 monomethylation in gene regulation	236	66	77	58	35
4vs4p782	Endosomal escape of RNA therapeutics: How do we solve this rate-limiting problem?	236	130	32	49	25
8f133727	SREBP1 Contributes to Resolution of Pro-inflammatory TLR4 Signaling by Reprogramming Fatty Acid Metabolism	235	69	96	37	33
20t6f25j	Rebuilding Chromosomes After Catastrophe: Emerging Mechanisms of Chromothripsis	232	46	87	58	41
13v7056h	Identification of the bacteriophage nucleus protein interaction network	231	84	71	44	32

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