Department of Cellular & Molecular Medicine - Open Access Policy Deposits

eScholarship stats: History by Item for May through August, 2026

Item	Title	Total requests	2026-08	2026-07	2026-06	2026-05
7rs018c6	Gain-of-function cardiomyopathic mutations in RBM20 rewire splicing regulation and re-distribute ribonucleoprotein granules within processing bodies	751	29	33	50	639
0jb936p7	Mechanism of STMN2 cryptic splice-polyadenylation and its correction for TDP-43 proteinopathies	560	182	108	120	150
551458jj	APOE4/4 is linked to damaging lipid droplets in Alzheimer’s disease microglia	501	126	81	175	119
172879gx	Age-Dependent Brain Gene Expression and Copy Number Anomalies in Autism Suggest Distinct Pathological Processes at Young Versus Mature Ages	485	16	12	31	426
9wk3d379	Guidelines for the use and interpretation of assays for monitoring autophagy	484	130	109	117	128
9044v022	Brain organoids, consciousness, ethics and moral status	436	88	56	99	193
70c3m48j	Spindle assembly checkpoint activation and silencing at kinetochores	399	93	112	78	116
0914g67c	A comparative atlas of single-cell chromatin accessibility in the human brain	393	117	107	86	83
6nt244k4	Generation of ‘semi-guided’ cortical organoids with complex neural oscillations	379	184	64	57	74
00g3j9wp	Cryptic splicing of stathmin-2 and UNC13A mRNAs is a pathological hallmark of TDP-43-associated Alzheimer’s disease	366	70	68	99	129
4ch9n51h	Mitotic tethering enables inheritance of shattered micronuclear chromosomes	358	121	50	88	99
9742k8ch	Epistatic interactions between NMD and TRP53 control progenitor cell maintenance and brain size	358	56	62	119	121
4bd0d5ws	An environment-dependent transcriptional network specifies human microglia identity	353	110	60	102	81
2nz1949j	A large-scale binding and functional map of human RNA-binding proteins	346	74	56	99	117
8fz9q8fw	Lipid-associated macrophages’ promotion of fibrosis resolution during MASH regression requires TREM2	342	101	81	79	81
3pv76061	E-cigarettes compromise the gut barrier and trigger inflammation	336	84	67	92	93
01j548f4	Perspectives on ENCODE	335	67	130	52	86
0r30n2q3	Adipose tissue macrophages secrete small extracellular vesicles that mediate rosiglitazone-induced insulin sensitization	327	48	56	100	123
9093x51q	Complex Oscillatory Waves Emerging from Cortical Organoids Model Early Human Brain Network Development	324	164	43	53	64
4vs4p782	Endosomal escape of RNA therapeutics: How do we solve this rate-limiting problem?	320	98	60	130	32
2pp4w8dz	The complexity of tobacco smoke-induced mutagenesis in head and neck cancer	315	86	58	74	97
1jm982xv	Decoding ALS: from genes to mechanism	307	79	40	105	83
1m706149	Reversing a model of Parkinson’s disease with in situ converted nigral neurons	304	84	46	77	97
3cv2t1d1	Mechanism and reconstitution of circadian transcription in cyanobacteria	303	57	54	77	115
10h0243m	Sequential membrane- and protein-bound organelles compartmentalize genomes during phage infection	301	52	59	98	92
28k88901	Transcription Factor 4 loss-of-function is associated with deficits in progenitor proliferation and cortical neuron content	292	41	65	75	111
27v4m3md	Role of H3K4 monomethylation in gene regulation	287	77	67	66	77
0qp9m9t3	The phage nucleus synergizes with an anti-defense protein to resist bacterial immunity	284	70	13	47	154
5s47j042	First Organoid Intelligence (OI) workshop to form an OI community	283	47	34	74	128
2bq0m1f2	Reduced signal for polygenic adaptation of height in UK Biobank	265	47	37	82	99
219597nn	Zika Virus Targets Glioblastoma Stem Cells through a SOX2-Integrin αvβ5 Axis	261	109	36	53	63
4vt1n111	A phage nucleus-associated RNA-binding protein is required for jumbo phage infection	257	58	37	77	85
68k9w7dj	A living organoid biobank of patients with Crohn’s disease reveals molecular subtypes for personalized therapeutics	257	63	46	65	83
2x41m3mj	DNA damage and somatic mutations in mammalian cells after irradiation with a nail polish dryer	252	68	72	59	53
9jp3g347	The SARS-CoV-2 nucleocapsid phosphoprotein forms mutually exclusive condensates with RNA and the membrane-associated M protein	250	45	40	57	108
6c8813mk	ApoC-III inhibits clearance of triglyceride-rich lipoproteins through LDL family receptors	248	45	53	47	103
6z9096mf	An in vivo neuroimmune organoid model to study human microglia phenotypes	247	87	36	55	69
7m89k316	Nuclear miR-320 Mediates Diabetes-Induced Cardiac Dysfunction by Activating Transcription of Fatty Acid Metabolic Genes to Cause Lipotoxicity in the Heart	247	38	30	125	54
8f133727	SREBP1 Contributes to Resolution of Pro-inflammatory TLR4 Signaling by Reprogramming Fatty Acid Metabolism	239	53	21	69	96
0503r9x1	Adult stem cell-derived complete lung organoid models emulate lung disease in COVID-19	238	47	45	65	81
13j4f1fx	Author Correction: Expanded encyclopaedias of DNA elements in the human and mouse genomes	238	49	72	70	47
3pd6q5r4	Promoter-proximal CTCF binding promotes distal enhancer-dependent gene activation	237	39	60	71	67
2hg812wf	Synaptogenesis: unmasking molecular mechanisms using Caenorhabditis elegans.	236	52	30	77	77
5s6754zv	A phenotypic spectrum of autism is attributable to the combined effects of rare variants, polygenic risk and sex	234	98	30	49	57
1rw4q1rv	Integrative analysis of the 3D genome and epigenome in mouse embryonic tissues	232	34	66	57	75
4bc6c9wg	Exposure of iPSC-derived human microglia to brain substrates enables the generation and manipulation of diverse transcriptional states in vitro	230	65	45	69	51
8670n4cq	Three-dimensional bioprinted glioblastoma microenvironments model cellular dependencies and immune interactions	229	86	18	63	62
3mk2678t	Exploring the consequences of redirecting an exocytic Rab onto endocytic vesicles	228	29	43	73	83
1qp1x4zx	A C6orf10/LOC101929163 locus is associated with age of onset in C9orf72 carriers	225	130	13	17	65
77f9r1t7	Drug repurposing screens identify chemical entities for the development of COVID-19 interventions	223	76	30	54	63

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