Department of Pharmacology - Open Access Policy Deposits

eScholarship stats: History by Item for June through September, 2026

Item	Title	Total requests	2026-09	2026-08	2026-07	2026-06
5d7263c4	Biology and therapeutic targeting of vascular endothelial growth factor A	1,039	208	344	339	148
9n50z8bh	Oxidized DNA fragments exit mitochondria via mPTP- and VDAC-dependent channels to activate NLRP3 inflammasome and interferon signaling	934	195	307	214	218
6xh967hx	Targeting angiogenesis in oncology, ophthalmology and beyond	652	177	218	125	132
9g90f6cs	ATF4 suppresses hepatocarcinogenesis by inducing SLC7A11 (xCT) to block stress-related ferroptosis	572	167	205	102	98
75g75986	Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)	564	84	110	173	197
29g1715t	Omega-3 fatty acids cause dramatic changes in TLR4 and purinergic eicosanoid signaling	541	464	32	16	29
73w1p39v	NF-κB Restricts Inflammasome Activation via Elimination of Damaged Mitochondria	522	80	192	80	170
2j33z2pc	mTOR: a pharmacologic target for autophagy regulation	518	71	98	125	224
1676z83d	Mitochondrial quality control in cardiomyocytes: safeguarding the heart against disease and ageing	467	134	108	92	133
5hq8g0ws	The metabolic basis of epilepsy	439	81	191	83	84
9wk3d379	Guidelines for the use and interpretation of assays for monitoring autophagy	439	83	130	109	117
8kq945z6	G Protein-Coupled Receptors as Targets for Approved Drugs: How Many Targets and How Many Drugs?	419	90	132	64	133
8fc8m0vp	Ten years of anti-vascular endothelial growth factor therapy	410	86	131	100	93
4n86z018	Acetylation Stabilizes ATP-Citrate Lyase to Promote Lipid Biosynthesis and Tumor Growth	392	39	160	88	105
2tp17155	The tubular hypothesis of nephron filtration and diabetic kidney disease	388	120	98	68	102
2p8330nb	Autophagy, NLRP3 inflammasome and auto-inflammatory/immune diseases.	373	69	153	82	69
6476p3bg	Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018	370	54	103	85	128
7nd4h9bf	Structural insights into GABAA receptor potentiation by Quaalude.	362	101	121	49	91
60s3m5b7	A comprehensive classification system for lipids 1	343	40	63	31	209
36g9c05z	Development of SGLT1 and SGLT2 inhibitors	328	77	100	51	100
9pk7p6n1	Sensory specializations drive octopus and squid behaviour	325	133	98	50	44
3hw6q79p	Molecular profiling of cancer patients enables personalized combination therapy: the I-PREDICT study	320	90	87	44	99
0285358r	The Tabula Sapiens: A multiple-organ, single-cell transcriptomic atlas of humans	314	83	69	88	74
56n8q85q	Liquid–liquid phase separation drives cellular function and dysfunction in cancer	312	66	92	64	90
7hc1r9g2	Dll4 and Notch signalling couples sprouting angiogenesis and artery formation	312	74	74	69	95
79w4r3qf	The tumor-sentinel lymph node immuno-migratome reveals CCR7⁺ dendritic cells drive response to sequenced immunoradiotherapy	307	75	139	51	42
46z4z71k	Efficacy of dietary odd-chain saturated fatty acid pentadecanoic acid parallels broad associated health benefits in humans: could it be essential?	305	84	46	44	131
7g17d5p9	Phospholipase A2 Enzymes: Physical Structure, Biological Function, Disease Implication, Chemical Inhibition, and Therapeutic Intervention	305	66	86	54	99
9vm5290q	Molecular Spies in Action: Genetically Encoded Fluorescent Biosensors Light up Cellular Signals	303	77	74	66	86
8q63m69f	Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking	299	64	64	67	104
6nr1f8xv	Structural basis of sensory receptor evolution in octopus	297	101	113	36	47
3wn6t7m1	Insulin signaling in health and disease	268	49	47	119	53
2sg8v2pf	Increased Adipocyte O2 Consumption Triggers HIF-1α, Causing Inflammation and Insulin Resistance in Obesity	265	62	68	51	84
9cw614g4	Glucose transporters in the kidney in health and disease	264	66	69	54	75
00j856g9	Disruption of the HER3-PI3K-mTOR oncogenic signaling axis and PD-1 blockade as a multimodal precision immunotherapy in head and neck cancer	260	35	52	69	104
45b1h5kr	Structure of an endosomal signaling GPCR–G protein–β-arrestin megacomplex	260	78	53	46	83
0qg2q8x7	Eicosanoid storm in infection and inflammation	255	57	76	44	78
4jv6b7cz	CD301b+ monocyte-derived dendritic cells mediate resistance to radiotherapy	253	39	55	61	98
4m59v2tf	Illuminating G-Protein-Coupling Selectivity of GPCRs	251	68	90	46	47
881291j7	Multi-omics analyses of the ulcerative colitis gut microbiome link Bacteroides vulgatus proteases with disease severity	246	58	86	39	63
4z04x122	Regulation of epithelial-mesenchymal transition by tumor microenvironmental signals and its implication in cancer therapeutics	245	38	91	46	70
455403xb	Update on Epithelial-Mesenchymal Plasticity in Cancer Progression	243	34	60	37	112
6ps428sf	Phospholipase A2 structure/function, mechanism, and signaling 1	242	55	79	45	63
5qg4j1v0	New mitochondrial DNA synthesis enables NLRP3 inflammasome activation	238	65	66	29	78
191702zj	YAP-driven malignant reprogramming of oral epithelial stem cells at single cell resolution	237	57	56	44	80
0137v246	Diversity of group types, regulation, and function of phospholipase A2.	234	15	88	94	37
06s546d8	RAP2 mediates mechanoresponses of the Hippo pathway	234	69	65	39	61
3fd886gm	Transcriptional signature primes human oral mucosa for rapid wound healing	231	46	69	48	68
2bp9760n	Sphingosine 1-phosphate receptor 3 and RhoA signaling mediate inflammatory gene expression in astrocytes	228	126	56	22	24
7zw251q9	Post-Translational Modifications of G Protein–Coupled Receptors Control Cellular Signaling Dynamics in Space and Time	228	54	65	49	60

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