Department of Pharmacology - Open Access Policy Deposits

eScholarship stats: History by Item for August through November, 2024

Item	Title	Total requests	2024-11	2024-10	2024-09	2024-08
75g75986	Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)	206	68	48	37	53
8fc8m0vp	Ten years of anti-vascular endothelial growth factor therapy	125	33	25	25	42
5d7263c4	Biology and therapeutic targeting of vascular endothelial growth factor A	108	17	31	27	33
0vm1v0gj	Diet and feeding pattern modulate diurnal dynamics of the ileal microbiome and transcriptome	103	20	28	23	32
62t387t8	Elemental mapping of labelled biological specimens at intermediate energy loss in an energy‐filtered TEM acquired using a direct detection device	102	13	25	15	49
6xh967hx	Targeting angiogenesis in oncology, ophthalmology and beyond	99	16	28	27	28
4rs605rx	Targeting cancer-promoting inflammation — have anti-inflammatory therapies come of age?	98	19	23	17	39
4fs2s75z	Mst1 shuts off cytosolic antiviral defense through IRF3 phosphorylation	94	10	25	17	42
7zm3p2t3	Monomethyl auristatin antibody and peptide drug conjugates for trimodal cancer chemo-radio-immunotherapy	93	21	19	18	35
53n226ft	Update on LIPID MAPS classification, nomenclature, and shorthand notation for MS-derived lipid structures.	91	25	23	16	27
9nb778dz	A COMPREHENSIVE CLASSIFICATION SYSTEM FOR LIPIDS	90	11	20	17	42
5hd2t522	Phospholipase A<sub>2</sub> catalysis and lipid mediator lipidomics.	88	19	18	16	35
96c976xw	N-Acylated and N-Alkylated 2-Aminobenzothiazoles Are Novel Agents That Suppress the Generation of Prostaglandin E2	82	13	22	13	34
50w2z43f	Transcriptional repression of estrogen receptor alpha by YAP reveals the Hippo pathway as therapeutic target for ER+ breast cancer	81	15	19	14	33
531097kr	Intracellular cyclic AMP not calcium, determines the direction of vesicle movement in melanophores: direct measurement by fluorescence ratio imaging	81	17	23	12	29
3rf5c285	Co‐occurrence of BAP1 and SF3B1 mutations in uveal melanoma induces cellular senescence	80	14	24	16	26
4681j0q9	Obesity causes mitochondrial fragmentation and dysfunction in white adipocytes due to RalA activation	79	25	16	6	32
7c7835rj	A tumor-penetrating peptide enhances circulation-independent targeting of peritoneal carcinomatosis	79	14	28	16	21
7rx412x7	Naturally occurring combinations of receptors from single cell transcriptomics in endothelial cells.	79	17	24	17	21
7dq0974t	Structure-guided development of selective M3 muscarinic acetylcholine receptor antagonists	78	20	19	17	22
2cz6r7bk	VEGF in Signaling and Disease: Beyond Discovery and Development	76	15	30	21	10
5pm377rh	A General Method for Site Specific Fluorescent Labeling of Recombinant Chemokines	76	19	24	16	17
1971215t	The mood stabilizer valproic acid opposes the effects of dopamine on circadian rhythms	72	10	17	11	34
7hc1r9g2	Dll4 and Notch signalling couples sprouting angiogenesis and artery formation	71	20	26	12	13
2ff6d48r	Outtakes from My Journey through the World of LIPID MAPS	67	12	15	15	25
7vz7q3kn	mTORC1 underlies age‐related muscle fiber damage and loss by inducing oxidative stress and catabolism	66	12	18	11	25
6p49073g	Phosphatidylinositol metabolism, phospholipases, lipidomics, and cancer: In Memoriam: Michael J. O. Wakelam (1955-2020).	65	10	25	10	20
5hq8g0ws	The metabolic basis of epilepsy	58	7	8	15	28
06s546d8	RAP2 mediates mechanoresponses of the Hippo pathway	56	6	16	9	25
46z4z71k	Efficacy of dietary odd-chain saturated fatty acid pentadecanoic acid parallels broad associated health benefits in humans: could it be essential?	55	5	10	6	34
0f31h0p2	Targeted Reversible Covalent Modification of a Noncatalytic Lysine of the Krev Interaction Trapped 1 Protein Enables Site-Directed Screening for Protein–Protein Interaction Inhibitors	52	52
3km8b1x7	Metformin inhibition of mitochondrial ATP and DNA synthesis abrogates NLRP3 inflammasome activation and pulmonary inflammation	49	8	18	7	16
7ft8k6j6	Deciphering Off-Target Effects in CRISPR-Cas9 through Accelerated Molecular Dynamics.	49	2	11	4	32
1pz617gs	Choline Uptake and Metabolism Modulate Macrophage IL-1β and IL-18 Production	48	1	8	3	36
6q43r01w	Regulation of Hippo pathway transcription factor TEAD by p38 MAPK-induced cytoplasmic translocation	48	3	11	6	28
9pr4k9zz	Cathepsin B in neurodegeneration of Alzheimer's disease, traumatic brain injury, and related brain disorders	48	9	7	3	29
1g79r0zt	NRF2 as a regulator of cell metabolism and inflammation in cancer	47	1	8	11	27
443152c0	Angiotensin II receptor inhibition ameliorates liver fibrosis and enhances hepatocellular carcinoma infiltration by effector T cells.	47	3	5	3	36
4sf2h363	Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance	47	3	7	7	30
2p8330nb	Autophagy, NLRP3 inflammasome and auto-inflammatory/immune diseases.	46	15	11	8	12
881291j7	Multi-omics analyses of the ulcerative colitis gut microbiome link Bacteroides vulgatus proteases with disease severity	46	5	12	3	26
28b095rh	MON-009 GLUT1-Mediated Glycolysis Facilitates GnRH-Induced Secretion of Luteinizing Hormone	45	6	7	4	28
80p2q1dm	Fructose stimulated de novo lipogenesis is promoted by inflammation	45	8	5	5	27
9j97n3xr	Dilated cardiomyopathy mutation in beta-cardiac myosin enhances actin activation of the power stroke and phosphate release	45	2	4	7	32
5mx5r53d	β3-adrenergic receptor downregulation leads to adipocyte catecholamine resistance in obesity	44	8	10	10	16
7gv3m9x3	Sodium glucose cotransporter SGLT1 as a therapeutic target in diabetes mellitus	44	10	7	5	22
348171f0	The GPCR–Gαs–PKA signaling axis promotes T cell dysfunction and cancer immunotherapy failure	43	2	16	1	24
56n8q85q	Liquid-liquid phase separation drives cellular function and dysfunction in cancer.	43	9	6	6	22
8d83w75t	Brief history of anti‐seizure drug development	43	9	9	4	21
6ws1s4jx	CNS fibroblasts form a fibrotic scar in response to immune cell infiltration	42	1	6	3	32

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