Sebaceous hyperplasia, a benign proliferation ofsebaceous glands, has been well documented inorgan transplant recipients treated with cyclosporine.Sebaceous hyperplasia has not been stronglyassociated with any other immunosuppressivemedications. We report a case of eruptive sebaceoushyperplasia in a renal transplant recipient with noprevious exposure to cyclosporine that was recentlystarted on tacrolimus, mycophenolate mofetil, andprednisone. To our knowledge, this is the first report oferuptive sebaceous hyperplasia in a renal transplantrecipient who was immunosuppressed withtacrolimus and had no prior exposure to cyclosporine