Melanoma is the 5th most common cancer in the United States and is curable if detected early. Identifying disparities in melanoma incidence may guide public health initiatives and improve outcomes.Melanoma is most common in non-Hispanic White (NHW) patients, but other racial and ethnic groups are more often diagnosed at late-stage disease and experience higher mortality than NHW patients.Higher melanoma incidence has been reported in rural than in urban settings, but the intersection of rurality with race and ethnicity has not been thoroughly explored.This study examines melanoma incidence, stratified by rural-urban residence and race and ethnicity, to identify populations experiencing disproportionately heightened melanoma burden.