Motivated by recent progress in studies of the high-$z$ Universe, we build a
new model for the global 21-cm signal that is explicitly calibrated to
measurements of the galaxy luminosity function (LF) and further tuned to match
the Thomson scattering optical depth of the cosmic microwave background,
$\tau_e$. Assuming that the $z \lesssim 8$ galaxy population can be smoothly
extrapolated to higher redshifts, the recent decline in best-fit values of
$\tau_e$ and the inefficient heating induced by X-ray binaries (HMXBs; the
presumptive sources of the X-ray background at high-$z$) imply that the
entirety of cosmic reionization and reheating occurs at redshifts $z \lesssim
12$. In contrast to past global 21-cm models, whose $z \sim 20$ ($
u \sim 70$
MHz) absorption features and strong $\sim 25$ mK emission features were driven
largely by the assumption of efficient early star-formation and X-ray heating,
our new fiducial model peaks in absorption at $
u \sim 110$ MHz at a depth of
$\sim -160$ mK and has a negligible emission component. As a result, a strong
emission signal would provide convincing evidence that HMXBs are not the only
drivers of cosmic reheating. Shallow absorption troughs should accompany strong
heating scenarios, but could also be caused by a low escape fraction of
Lyman-Werner photons. Generating signals with troughs at $
u \lesssim 95$ MHz
requires a floor in the star-formation efficiency in halos below $\sim 10^{9}
M_{\odot}$, which is equivalent to steepening the faint-end of the galaxy LF.
These findings demonstrate that the global 21-cm signal is a powerful
complement to current and future galaxy surveys and efforts to better
understand the interstellar medium in high-$z$ galaxies.