The ocelot (Leopardus pardalis) is an endangered cat with less than 120 individuals remaining in the United States. Ocelot roadkills are an important problem potentially threatening ocelot persistence in southern Texas. Landscape planning can provide options for the resolution of traffic-ocelot conflicts. We suggest several conservation strategies and tactics involving important road-habitat interfaces, road underpasses, and fences. Support of alternative recovery strategies (e.g., habitat restoration) may help offset ocelot roadkills, particularly along road segments where practical management is not effective.