Topology has become increasingly important in the study of many-body quantum mechanics, in both high energy and condensed matter applications. While the importance of smooth topology has long been appreciated in this context, especially with the rise of index theory, torsion phenomena and discrete group symmetries are relatively new directions. In this thesis, I collect some mathematical results and conjectures that I have encountered in the exploration of these new topics. I also give an introduction to some quantum field theory topics I hope will be accessible to topologists.