This study investigates the associations between self-assessed adverse labor market events (experiencing problems with coworkers, employment changes, financial strain) and health. Longitudinal data are obtained from the National Epidemiological Survey of Alcohol and Related Conditions. Our findings suggest problems with coworkers, employment changes, and financial strain are associated, respectively, with a 3.1 percent (3.3 percent), 0.9 percent (0.2 percent), and 4.5 percent (5.1 percent) reduction in mental health among men (women). Associations are smaller in magnitude and less significant for physical health.