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Total Synthesis of (+)-Resiniferatoxin and Studies Toward the Total Synthesis of 1-Alkyl Daphnanes
- Spessert, Lukas
- Advisor(s): Maimone, Thomas J.
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Abstract
Resiniferatoxin (RTX, 1.1.1, Figure 1.1.1) belongs to the family of daphnane diterpene orthoesters (DDO’s), a structurally and biologically very diverse subfamily of the daphnane diterpene natural products of with over 200 members have been isolated to date