Department of Molecular and Medical Pharmacology, UCLA
Parent: UCLA
eScholarship stats: Breakdown by Item for June through September, 2024
Item | Title | Total requests | Download | View-only | %Dnld |
---|---|---|---|---|---|
54c114pc | Multivalent N‑Acetylgalactosamine-Conjugated siRNA Localizes in Hepatocytes and Elicits Robust RNAi-Mediated Gene Silencing | 220 | 90 | 130 | 40.9% |
1n83k1hm | The “cancer immunogram” | 205 | 48 | 157 | 23.4% |
0bh4n1vq | Targeted agents and immunotherapies: optimizing outcomes in melanoma. | 169 | 146 | 23 | 86.4% |
7q04w30c | What does PD-L1 positive or negative mean? | 139 | 100 | 39 | 71.9% |
4xj2w70k | Chapter Five Advances in PET Detection of the Antitumor T Cell Response | 134 | 118 | 16 | 88.1% |
03j4k0f6 | Single-cell RNA-seq analysis of the brainstem of mutant SOD1 mice reveals perturbed cell types and pathways of amyotrophic lateral sclerosis | 119 | 43 | 76 | 36.1% |
5h77d38w | Expert Perspectives on Controversies in Metastatic Castration-Resistant Prostate Cancer Management: Narrative Review and Report of the First US Prostate Cancer Conference Part 2. | 116 | 8 | 108 | 6.9% |
18p914db | Glioblastoma Utilizes Fatty Acids and Ketone Bodies for Growth Allowing Progression during Ketogenic Diet Therapy | 106 | 24 | 82 | 22.6% |
466365dq | Future perspectives in melanoma research: meeting report from the “Melanoma Bridge”: Napoli, December 3rd–6th 2014 | 105 | 20 | 85 | 19.0% |
21x3z6hr | Spartalizumab or placebo in combination with dabrafenib and trametinib in patients with BRAF V600-mutant melanoma: exploratory biomarker analyses from a randomized phase 3 trial (COMBI-i) | 104 | 18 | 86 | 17.3% |
5qc137rx | Dichloroacetate should be considered with platinum-based chemotherapy in hypoxic tumors rather than as a single agent in advanced non-small cell lung cancer. | 103 | 11 | 92 | 10.7% |
6dn6b8jq | Phase 3 multicenter randomized trial of PSMA PET/CT prior to definitive radiation therapy for unfavorable intermediate-risk or high-risk prostate cancer [PSMA dRT]: study protocol | 102 | 23 | 79 | 22.5% |
0sn523vw | Associations of immunological features with COVID-19 severity: a systematic review and meta-analysis | 101 | 17 | 84 | 16.8% |
0tp1638w | Dynamic Changes in the Subgingival Microbiome and Their Potential for Diagnosis and Prognosis of Periodontitis | 100 | 29 | 71 | 29.0% |
1wm4z4cd | Systematic transcriptome-wide meta-analysis across endocrine disrupting chemicals reveals shared and unique liver pathways, gene networks, and disease associations | 100 | 11 | 89 | 11.0% |
5qm5q3nv | Serum lipids are associated with nonalcoholic fatty liver disease: a pilot case-control study in Mexico | 99 | 9 | 90 | 9.1% |
9nh2d4t3 | The cardiomyocyte disrupts pyrimidine biosynthesis in non-myocytes to regulate heart repair | 99 | 17 | 82 | 17.2% |
0qv0707j | Mergeomics: a web server for identifying pathological pathways, networks, and key regulators via multidimensional data integration | 95 | 31 | 64 | 32.6% |
7jm3422h | PD-1 blockade induces responses by inhibiting adaptive immune resistance | 93 | 20 | 73 | 21.5% |
1dc6s7xj | The GSK3 Signaling Axis Regulates Adaptive Glutamine Metabolism in Lung Squamous Cell Carcinoma. | 92 | 10 | 82 | 10.9% |
9292w8n6 | Multiple early factors anticipate post-acute COVID-19 sequelae | 91 | 48 | 43 | 52.7% |
3gk1p7kf | PSMA PET validates higher rates of metastatic disease for European Association of Urology Biochemical Recurrence Risk Groups: an international multicenter study | 90 | 17 | 73 | 18.9% |
9qd4738k | Loss of rps9 in Zebrafish Leads to p53-Dependent Anemia | 90 | 17 | 73 | 18.9% |
5st231s3 | Primary, Adaptive, and Acquired Resistance to Cancer Immunotherapy | 89 | 73 | 16 | 82.0% |
63q4v54c | β-Globin Lentiviral Vectors Have Reduced Titers due to Incomplete Vector RNA Genomes and Lowered Virion Production | 89 | 8 | 81 | 9.0% |
38x6x4vz | Generation of mature T cells from human hematopoietic stem and progenitor cells in artificial thymic organoids | 88 | 10 | 78 | 11.4% |
3bg4h9n7 | Five-year survival outcomes for patients with advanced melanoma treated with pembrolizumab in KEYNOTE-001 | 88 | 4 | 84 | 4.5% |
1pc070cw | Identification and validation of genes affecting aortic lesions in mice | 86 | 5 | 81 | 5.8% |
5jv9f3s6 | Genome-Wide RNAi High-Throughput Screen Identifies Proteins Necessary for the AHR-Dependent Induction of CYP1A1 by 2,3,7,8-Tetrachlorodibenzo-p-dioxin | 86 | 19 | 67 | 22.1% |
92m8q260 | Anti-programmed cell death protein-1/ligand-1 therapy in different cancers | 86 | 6 | 80 | 7.0% |
61c3v6b7 | Interferon-mediated reprogramming of membrane cholesterol to evade bacterial toxins | 85 | 8 | 77 | 9.4% |
46k1r1zp | 5-(2-[18 F]Fluoroethyl)-4-Methylthiazole Probe For Positron Emission Tomography Of The Central Nervous System | 84 | 18 | 66 | 21.4% |
8p963376 | Biglycan gene connects metabolic dysfunction with brain disorder. | 84 | 13 | 71 | 15.5% |
9h88g674 | Improved Leakage Correction for Single-Echo Dynamic Susceptibility Contrast Perfusion MRI Estimates of Relative Cerebral Blood Volume in High-Grade Gliomas by Accounting for Bidirectional Contrast Agent Exchange. | 84 | 22 | 62 | 26.2% |
3vk9k174 | Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles | 83 | 10 | 73 | 12.0% |
50n903xc | Ipilimumab alone or in combination with nivolumab in patients with advanced melanoma who have progressed or relapsed on PD-1 blockade: clinical outcomes and translational biomarker analyses | 83 | 5 | 78 | 6.0% |
5410d0x6 | Relative contributions of sex hormones, sex chromosomes, and gonads to sex differences in tissue gene regulation | 83 | 9 | 74 | 10.8% |
3k646152 | Utomilumab in Patients With Immune Checkpoint Inhibitor-Refractory Melanoma and Non-Small-Cell Lung Cancer | 81 | 7 | 74 | 8.6% |
3t8708z1 | Single cell analysis reveals immune cell–adipocyte crosstalk regulating the transcription of thermogenic adipocytes | 81 | 16 | 65 | 19.8% |
2t45m6gj | Clinical and Genomic Characterization of Treatment-Emergent Small-Cell Neuroendocrine Prostate Cancer: A Multi-institutional Prospective Study. | 80 | 8 | 72 | 10.0% |
668692jt | Genetic engineering of hematopoietic stem cells to generate invariant natural killer T cells | 80 | 9 | 71 | 11.3% |
8v80b071 | A novel multi-reaction microdroplet platform for rapid radiochemistry optimization | 80 | 3 | 77 | 3.8% |
6867n8kj | Hydrogel Arrays Enable Increased Throughput for Screening Effects of Matrix Components and Therapeutics in 3D Tumor Models. | 79 | 8 | 71 | 10.1% |
2gn1f3nr | Future perspectives in melanoma research: meeting report from the "Melanoma Bridge", Napoli, December 5th-8th 2013 | 78 | 5 | 73 | 6.4% |
04m512v0 | 4-(Nitrophenylsulfonyl)piperazines mitigate radiation damage to multiple tissues | 75 | 11 | 64 | 14.7% |
7h17w53v | The DNA methylation landscape of advanced prostate cancer | 74 | 35 | 39 | 47.3% |
9jm2w1xh | Gene editing: Towards the third generation of adoptive T-cell transfer therapies | 74 | 5 | 69 | 6.8% |
58f7q1rt | Cannabis effects on brain structure, function, and cognition: considerations for medical uses of cannabis and its derivatives | 71 | 50 | 21 | 70.4% |
6t49338z | The whole-genome landscape of medulloblastoma subtypes | 71 | 27 | 44 | 38.0% |
53j8v4ft | Deferred use of bevacizumab for recurrent glioblastoma is not associated with diminished efficacy | 70 | 7 | 63 | 10.0% |
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