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Generation of mature T cells from human hematopoietic stem and progenitor cells in artificial thymic organoids
- Seet, Christopher S;
- He, Chongbin;
- Bethune, Michael T;
- Li, Suwen;
- Chick, Brent;
- Gschweng, Eric H;
- Zhu, Yuhua;
- Kim, Kenneth;
- Kohn, Donald B;
- Baltimore, David;
- Crooks, Gay M;
- Montel-Hagen, Amélie
Published Web Location
https://doi.org/10.1038/nmeth.4237Abstract
This paper describes an in vitro method to generate human T cells from hematopoietic stem and progenitor cells (HSPCs). It should be useful for both basic and applied studies using T cells.
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