Open Access Policy Deposits

eScholarship stats: Breakdown by Item for May through August, 2026

Item	Title	Total requests	Download	View-only	%Dnld
75g75986	Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)	646	457	189	70.7%
6x66v4k6	Sperm tsRNAs contribute to intergenerational inheritance of an acquired metabolic disorder	598	196	402	32.8%
2bw6886v	Domain Structure of the Dnmt1, Dnmt3a, and Dnmt3b DNA Methyltransferases	543	260	283	47.9%
80m7x5x5	Diet high in linoleic acid dysregulates the intestinal endocannabinoid system and increases susceptibility to colitis in Mice	542	116	426	21.4%
4mw725pz	scDesign2: a transparent simulator that generates high-fidelity single-cell gene expression count data with gene correlations captured	533	65	468	12.2%
87f229pf	PANDORA-seq expands the repertoire of regulatory small RNAs by overcoming RNA modifications	428	240	188	56.1%
7c175873	Virus infection triggers widespread silencing of host genes by a distinct class of endogenous siRNAs in Arabidopsis	408	347	61	85.0%
90k2q84m	Pan-cancer analyses reveal cancer-type-specific fungal ecologies and bacteriome interactions	404	195	209	48.3%
9sg3c84v	Fungi are key players in extreme ecosystems	401	247	154	61.6%
98r4f90g	Cotton plants export microRNAs to inhibit virulence gene expression in a fungal pathogen	389	196	193	50.4%
1ck54309	Disruption of electrostatic contacts in the HNH nuclease from a thermophilic Cas9 rewires allosteric motions and enhances high-temperature DNA cleavage	386	326	60	84.5%
0z5275h1	Superstable lipid vacuoles endow cartilage with its shape and biomechanics	369	206	163	55.8%
1fk6h277	Immune suppressive landscape in the human esophageal squamous cell carcinoma microenvironment	369	53	316	14.4%
5712r9nz	TNRC18 engages H3K9me3 to mediate silencing of endogenous retrotransposons	368	150	218	40.8%
8zv742pc	Pre-Cambrian roots of novel Antarctic cryptoendolithic bacterial lineages	360	274	86	76.1%
9742k8ch	Epistatic interactions between NMD and TRP53 control progenitor cell maintenance and brain size	358	281	77	78.5%
72z114g5	DNA-binding protein PfAP2-P regulates parasite pathogenesis during malaria parasite blood stages	357	206	151	57.7%
3v81t4m7	Comprehensive Characterization of Cancer Driver Genes and Mutations	340	113	227	33.2%
4zf8m9m5	Current state and future prospects of spatial biology in colorectal cancer	331	89	242	26.9%
7gs1w3pb	A chromosome conformation capture ordered sequence of the barley genome	324	202	122	62.3%
9d4967pm	Drug target prediction through deep learning functional representation of gene signatures	316	136	180	43.0%
7wn084zt	A view of the pan‐genome of domesticated Cowpea (Vigna unguiculata [L.] Walp.)	312	172	140	55.1%
62n300tn	CLAVATA3 mediated simultaneous control of transcriptional and post-translational processes provides robustness to the WUSCHEL gradient	306	257	49	84.0%
4485m01m	The Fungal Tree of Life: from Molecular Systematics to Genome-Scale Phylogenies	304	215	89	70.7%
7924f58g	Chronic, Low-Dose Methamphetamine Reveals Sexual Dimorphism of Memory Performance, Histopathology, and Gene Expression Affected by HIV-1 Tat Protein in a Transgenic Model of NeuroHIV	292	238	54	81.5%
1nh662bs	Infection and inflammation stimulate expansion of a CD74+ Paneth cell subset to regulate disease progression	291	151	140	51.9%
08s0n0j5	Babesia duncani multi-omics identifies virulence factors and drug targets	281	146	135	52.0%
86x0713x	Fine-tuned protein language model identifies antigen-specific B cell receptors from immune repertoires	281	201	80	71.5%
4354m8h5	Enhancement of CRISPR/Cas12a trans-cleavage activity using hairpin DNA reporters	279	161	118	57.7%
2dk563d8	The structure of Haemophilus influenzae prephenate dehydrogenase suggests unique features of bifunctional TyrA enzymes	275	27	248	9.8%
37g3j4sb	Spray‐induced gene silencing for disease control is dependent on the efficiency of pathogen RNA uptake	269	144	125	53.5%
1dr6q4x6	Validating genome-wide CRISPR-Cas9 function improves screening in the oleaginous yeast Yarrowia lipolytica	268	131	137	48.9%
019146q9	Identification and phylogenetic analysis of RNA binding domain abundant in apicomplexans or RAP proteins	259	176	83	68.0%
71p5t489	Shed Light in the DaRk LineagES of the Fungal Tree of Life—STRES	258	174	84	67.4%
0036f4tg	Gaussian accelerated molecular dynamics: Principles and applications	253	86	167	34.0%
4mp2h2n6	Genome-scale phylogenetics reveals a monophyletic Zoopagales (Zoopagomycota, Fungi)	251	195	56	77.7%
5cj0z7jv	Specification and formation of the neural crest: Perspectives on lineage segregation	248	47	201	19.0%
0k2442c1	m1A in CAG repeat RNA binds to TDP-43 and induces neurodegeneration	239	142	97	59.4%
1bb6h6w3	Lactobacillus rhamnosus GG Stimulates Dietary Tryptophan-Dependent Production of Barrier-Protecting Methylnicotinamide	237	134	103	56.5%
5ps719v0	Widespread adenine N6-methylation of active genes in fungi	236	154	82	65.3%
1z2724ft	Sequencing the Genomes of the First Terrestrial Fungal Lineages: What Have We Learned?	234	191	43	81.6%
18k3s04n	Diversity of cytosine methylation across the fungal tree of life	231	147	84	63.6%
5cp4r84c	Characterization and structural basis of a lethal mouse-adapted SARS-CoV-2	228	178	50	78.1%
31m0z7qf	Mustache: multi-scale detection of chromatin loops from Hi-C and Micro-C maps using scale-space representation	227	92	135	40.5%
8v83t6ng	Extremophilic and extremotolerant fungi	227	88	139	38.8%
45z3n9fc	Psychoactive plant- and mushroom-associated alkaloids from two behavior modifying cicada pathogens	226	133	93	58.8%
5md5r8vx	YY1 interacts with guanine quadruplexes to regulate DNA looping and gene expression	225	79	146	35.1%
8qd430n4	EphB2 Signaling Is Implicated in Astrocyte-Mediated Parvalbumin Inhibitory Synapse Development	225	183	42	81.3%
68s498n4	Small RNA-based antimicrobial immunity	224	61	163	27.2%
7mc1m7pv	Fungal biodiversity and conservation mycology in light of new technology, big data, and changing attitudes	223	114	109	51.1%

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Note: Due to the evolving nature of web traffic, the data presented here should be considered approximate and subject to revision. Learn more.