Open Access Policy Deposits

eScholarship stats: History by Item for July through October, 2026

Item	Title	Total requests	2026-10	2026-09	2026-08	2026-07
80m7x5x5	Diet high in linoleic acid dysregulates the intestinal endocannabinoid system and increases susceptibility to colitis in Mice	732	75	257	339	61
6x66v4k6	Sperm tsRNAs contribute to intergenerational inheritance of an acquired metabolic disorder	562	145	116	172	129
2bw6886v	Domain Structure of the Dnmt1, Dnmt3a, and Dnmt3b DNA Methyltransferases	534	99	225	114	96
75g75986	Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)	469	102	84	110	173
7c175873	Virus infection triggers widespread silencing of host genes by a distinct class of endogenous siRNAs in Arabidopsis	456	24	87	336	9
9sg3c84v	Fungi are key players in extreme ecosystems	402	64	99	159	80
87f229pf	PANDORA-seq expands the repertoire of regulatory small RNAs by overcoming RNA modifications	391	110	92	117	72
4zf8m9m5	Current state and future prospects of spatial biology in colorectal cancer	382	121	67	149	45
8zv742pc	Pre-Cambrian roots of novel Antarctic cryptoendolithic bacterial lineages	360	146	80	62	72
98r4f90g	Cotton plants export microRNAs to inhibit virulence gene expression in a fungal pathogen	351	79	69	124	79
90k2q84m	Pan-cancer analyses reveal cancer-type-specific fungal ecologies and bacteriome interactions	348	74	65	142	67
2310v0bv	Vision, challenges and opportunities for a Plant Cell Atlas	338	164	78	31	65
3v81t4m7	Comprehensive Characterization of Cancer Driver Genes and Mutations	325	96	75	75	79
72z114g5	DNA-binding protein PfAP2-P regulates parasite pathogenesis during malaria parasite blood stages	323	96	71	77	79
4485m01m	The Fungal Tree of Life: from Molecular Systematics to Genome-Scale Phylogenies	320	121	77	85	37
37g3j4sb	Spray‐induced gene silencing for disease control is dependent on the efficiency of pathogen RNA uptake	299	126	50	81	42
5ps719v0	Widespread adenine N6-methylation of active genes in fungi	293	162	36	40	55
1z2724ft	Sequencing the Genomes of the First Terrestrial Fungal Lineages: What Have We Learned?	290	151	32	31	76
1dr6q4x6	Validating genome-wide CRISPR-Cas9 function improves screening in the oleaginous yeast Yarrowia lipolytica	289	132	52	49	56
1fk6h277	Immune suppressive landscape in the human esophageal squamous cell carcinoma microenvironment	286	52	44	144	46
0036f4tg	Gaussian accelerated molecular dynamics: Principles and applications	283	79	92	69	43
0z5275h1	Superstable lipid vacuoles endow cartilage with its shape and biomechanics	281	94	70	53	64
7gs1w3pb	A chromosome conformation capture ordered sequence of the barley genome	266	81	65	74	46
9d4967pm	Drug target prediction through deep learning functional representation of gene signatures	259	53	53	78	75
80s9k72v	An accurate and robust imputation method scImpute for single-cell RNA-seq data	256	106	96	36	18
1ck54309	Disruption of electrostatic contacts in the HNH nuclease from a thermophilic Cas9 rewires allosteric motions and enhances high-temperature DNA cleavage	252	61	46	73	72
6xr5x68f	Spray-Induced Gene Silencing: a Powerful Innovative Strategy for Crop Protection	246	89	72	51	34
7924f58g	Chronic, Low-Dose Methamphetamine Reveals Sexual Dimorphism of Memory Performance, Histopathology, and Gene Expression Affected by HIV-1 Tat Protein in a Transgenic Model of NeuroHIV	240	63	71	49	57
7s96k8nc	Phylogenomic analyses of non-Dikarya fungi supports horizontal gene transfer driving diversification of secondary metabolism in the amphibian gastrointestinal symbiont, Basidiobolus	238	144	36	16	42
38d0x4hb	Mycoparasites, Gut Dwellers, and Saprotrophs: Phylogenomic Reconstructions and Comparative Analyses of Kickxellomycotina Fungi	232	117	48	33	34
4dj0r8gp	Reversible Regulation of Promoter and Enhancer Histone Landscape by DNA Methylation in Mouse Embryonic Stem Cells	231	51	119	49	12
1cc083z4	METTL3 regulates viral m6A RNA modification and host cell innate immune responses during SARS-CoV-2 infection	230	40	102	53	35
71p5t489	Shed Light in the DaRk LineagES of the Fungal Tree of Life—STRES	229	127	20	31	51
1bb6h6w3	Lactobacillus rhamnosus GG Stimulates Dietary Tryptophan-Dependent Production of Barrier-Protecting Methylnicotinamide	228	54	61	69	44
4cx275jn	Three-dimensional modeling of the P. falciparum genome during the erythrocytic cycle reveals a strong connection between genome architecture and gene expression	226	152	31	30	13
2gr101xp	Phylogenomics of Endogonaceae and evolution of mycorrhizas within Mucoromycota	225	127	22	29	47
18k3s04n	Diversity of cytosine methylation across the fungal tree of life	223	113	32	32	46
86x0713x	Fine-tuned protein language model identifies antigen-specific B cell receptors from immune repertoires	220	60	59	53	48
0k2442c1	m1A in CAG repeat RNA binds to TDP-43 and induces neurodegeneration	219	75	32	55	57
2154f71k	Dynamic changes in human single-cell transcriptional signatures during fatal sepsis	219	60	69	60	30
4bj2f8d7	KDM6A facilitates Xist upregulation at the onset of X inactivation	218	38	54	96	30
31m0z7qf	Mustache: multi-scale detection of chromatin loops from Hi-C and Micro-C maps using scale-space representation	216	71	48	68	29
45z3n9fc	Psychoactive plant- and mushroom-associated alkaloids from two behavior modifying cicada pathogens	212	65	47	67	33
4mp2h2n6	Genome-scale phylogenetics reveals a monophyletic Zoopagales (Zoopagomycota, Fungi)	212	91	37	32	52
7ft8k6j6	Deciphering Off-Target Effects in CRISPR-Cas9 through Accelerated Molecular Dynamics.	210	102	46	18	44
5x97c8xp	Expression activation of over 70% of Chlamydia trachomatis genes during the first hour of infection	208	47	106	28	27
4n64r36r	Balanced Training Sets Improve Deep Learning-Based Prediction of CRISPR sgRNA Activity	206	70	57	45	34
7tk1x1nr	Phylogenomic Analysis of a 55.1-kb 19-Gene Dataset Resolves a Monophyletic Fusarium that Includes the Fusarium solani Species Complex.	206	49	68	46	43
7wn084zt	A view of the pan‐genome of domesticated Cowpea (Vigna unguiculata [L.] Walp.)	206	57	41	54	54
9fs9w67h	Neuroendocrinology and the Genetics of Obesity	206	45	78	56	27

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