Pregaming (a.k.a., "prepartying," "pre-funking," or "predrinking") consists of drinking before going to a social function or gathering where alcohol may or may not be served. Existing research suggests that pregaming in high school and pre-college (i.e., the period between high school graduation and the start of college) is widespread. Moreover, pregaming prevalence appears to rapidly increase after students graduate from high school and transition into college. Thus, the purpose of this brief review is threefold: (a) to summarize the existing (albeit limited) research on pregaming among high school students and incoming college freshmen, (b) to present an overview of the risk factors that have been identified for participation in pregaming, and (c) to discuss the implications for practice that may be particularly relevant for school-employed/affiliated nurses as well as health practitioners who work in college settings.