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Scholarly Works (1 results)

Article
Peer Reviewed

On-demand nanozyme signal enhancement at the push of a button for the improved detection of SARS-CoV-2 nucleocapsid protein in serum

Bradbury, Daniel W;
Trinh, Jasmine T;
Ryan, Milo J;
Cantu, Cassandra M;
Lu, Jiakun;
Nicklen, Frances D;
Du, Yushen;
Sun, Ren;
Wu, Benjamin M;
Kamei, Daniel T

UCLA Previously Published Works (2021)

We developed an innovative 3D printed casing that incorporates a lateral-flow immunoassay, dehydrated signal enhancement reagents, and a sealed buffer chamber. With only the push of a button for signal enhancement, our device detected the SARS-CoV-2 N-protein in 40 min at concentrations as low as 0.1 ng mL^-1 in undiluted serum.