Skip to main content
Download PDF
- Main
On-demand nanozyme signal enhancement at the push of a button for the improved detection of SARS-CoV-2 nucleocapsid protein in serum
- Bradbury, Daniel W;
- Trinh, Jasmine T;
- Ryan, Milo J;
- Cantu, Cassandra M;
- Lu, Jiakun;
- Nicklen, Frances D;
- Du, Yushen;
- Sun, Ren;
- Wu, Benjamin M;
- Kamei, Daniel T
Published Web Location
https://doi.org/10.1039/d1an01350eAbstract
We developed an innovative 3D printed casing that incorporates a lateral-flow immunoassay, dehydrated signal enhancement reagents, and a sealed buffer chamber. With only the push of a button for signal enhancement, our device detected the SARS-CoV-2 N-protein in 40 min at concentrations as low as 0.1 ng mL-1 in undiluted serum.
Many UC-authored scholarly publications are freely available on this site because of the UC's open access policies. Let us know how this access is important for you.