An important receiver operation is to detect the presence specific preamble signals with unknown delays in the presence of scattering, Doppler effects and carrier offsets. This task, referred to as "link acquisition", is typically a sequential search over the transmitted signal space. Recently, many authors have suggested applying sparse recovery algorithms in the context of similar estimation or detection problems. These works typically focus on the benefits of sparse recovery, but not generally on the cost brought by compressive sensing. Thus, our goal is to examine the trade-off in complexity and performance that is possible when using sparse recovery. To do so, we propose a sequential sparsity-aware compressive sampling (C-SA) acquisition scheme, where a compressive multi-channel sampling (CMS) front-end is followed by a sparsity regularized likelihood ratio test (SR-LRT) module. The proposed C-SA acquisition scheme borrows insights from the models studied in the context of sub-Nyquist sampling, where a minimal amount of samples is captured to reconstruct signals with Finite Rate of Innovation (FRI). In particular, we propose an A/D conversion front-end that maximizes a well-known probability divergence measure, the average Kullback-Leibler distance, of all the hypotheses of the SR-LRT performed on the samples. We compare the proposed acquisition scheme vis- {a}-vis conventional alternatives with relatively low computational cost, such as the Matched Filter (MF), in terms of performance and complexity.

Abstract

Despite considerable research efforts, pancreatic cancer is associated with a dire prognosis and a 5-year survival rate of only 10%. Early symptoms of the disease are mostly nonspecific. The premise of improved survival through early detection is that more individuals will benefit from potentially curative treatment. Artificial intelligence (AI) methodology has emerged as a successful tool for risk stratification and identification in general health care. In response to the maturity of AI, Kenner Family Research Fund conducted the 2020 AI and Early Detection of Pancreatic Cancer Virtual Summit (www.pdac-virtualsummit.org) in conjunction with the American Pancreatic Association, with a focus on the potential of AI to advance early detection efforts in this disease. This comprehensive presummit article was prepared based on information provided by each of the interdisciplinary participants on one of the 5 following topics: Progress, Problems, and Prospects for Early Detection; AI and Machine Learning; AI and Pancreatic Cancer-Current Efforts; Collaborative Opportunities; and Moving Forward-Reflections from Government, Industry, and Advocacy. The outcome from the robust Summit conversations, to be presented in a future white paper, indicate that significant progress must be the result of strategic collaboration among investigators and institutions from multidisciplinary backgrounds, supported by committed funders.