1. Recordings from single axons of retinal ganglion cells in the rat's optic tract were used to determine whether bleaching a small area of the receptive field reduced sensitivity globally or locally, near the bleached photoreceptors. 2. When a suprathreshold test spot was alternated between two equally sensitive positions, the ganglion cell gave an approximately balanced response. The balance was upset if a small-spot bleach was selectively applied to one position. Recovery of the balanced condition was rapid. 3. Varying the duration of a constant illuminance bleach varied the duration of the imbalance following the bleach. 4. The recovery of sensitivity after small-spot bleaches was measured both at the location of the bleach and also at another location, initially equally sensitive. The recovery at the bleached location lagged recovery at the unbleached location; but even in the bleached location, the return of sensitivity was rapid. 5. Recovery of sensitivity after half-field bleaches was measured in the bleached and unbleached halves of the receptive field. Recovery in the bleached half lagged that in the unbleached half. 6. A comparison between the effects of a small-spot bleach and a half-field bleach of the same strength show that the duration of dark adaptation depends on the area of the bleach.

1. Responses from axons of single retinal ganglion cells in the rat's optic tract were used to measure the pooling of adaptive signals within the cells' receptive field. Computer-aided analyses of response measurements were used to evaluate sensitivity at a number of field locations. 2. A small adapting spot caused a localized decrease in sensitivity within the receptive field centre of ON- and OFF-centre ganglion cells. 2. The functions describing response versus test luminance were similar in shape for all test and adaptation configurations. This assured that, using a fixed criterion response, sensitivity determinations could be made just as well in any receptive field location and under any of the experimental conditions. 4. A concentric surround, antagonistic to the receptive field centre, was readily apparent only under conditions of light adaptation. Experiments on the local effects of small adapting spots, conducted with selective surround adaptation, showed that the non-uniform spread of adaptation within the receptive field centre was not linked to surround intrusion. 5. The possibility that the photopic mechanism intruded to contaminate these results was considered and rejected. 6. When a suprathreshold spot was alternated between two equally sensitive positions, the ganglion cell gave an approximately balanced response. An upset of this balance was produced by placing a small adapting spot at either position, thus demonstrating, in another way, the non-uniform spread of adaptation within the receptive field centre. 7. It is concluded that significant pooling of adaptation effects occurs prior to the combination of influences which contribute to the centre response of a ganglion cell.

1. Recordings from single axons of retinal ganglion cells in the rat's optic tract in response to small flashing test lights were used to follow the course of dark adaptation after exposing half of the receptive field to a bleaching light. 2. The recovery of log sensitivity followed an exponential time course in the exposed and unexposed half-fields. The curves had different time constants, with the exposed side taking longer to recover. 3. The time constants of recovery were increasing functions of exposure, but the rate of increase was different in the exposed and the unexposed half-fields. Direct exposure increased the time constant at a greater rate than did indirect exposure. 4. Comparison of the time constants of recovery in the exposed half-fields with those for pigment regeneration suggests that sensitivity recovers with the time course of rhodopsin regeneration. 5. Increment thresholds were determined using steady backgrounds which illuminated half of the receptive field. A greater threshold elevation was produced in the directly illuminated half-field compared with the half-field illuminated only by scattered light. Comparisons of the threshold-raising capacity of direct and indirect illumination were used to establish an 'upper bound' on the magnitude of light scatter. The time courses of the recovery of sensitivity after two different bleaches were compared. First, thresholds were measured in the unexposed half-field after a half-field bleach. Secondly the recovery of sensitivity after direct bleaching-exposure to the predetermined scatter upper bound' was measured. Recovery was more rapid in the latter case than the former, thus indicating that adaptation spreads laterally via some process other than light scattering.