NOvA is a long baseline neutrino experiment with an 810 km baseline, using the NuMIbeam at Fermilab, and a functionally identical near and far detector operating at an angle 14 mrad off axis from the beam. NOvA jointly measures muon neutrino (and antineutrino) disappearance and electron neutrino (and antineutrino) appearance to make a measurement of sin2θ23, δCP, and ∆m2 32, including its sign, the mass ordering. This dissertation reports a new measurement from NOvA, using 10 years of data, with a total exposure of 26.6 ×1020 POT of neutrino beam and 12.5 ×1020 POT of antineutrino beam. This represents 95.6% more neutrino beam exposure since the last NOvA analysis. Aspects of the analysis are discussed in detail, including neutrino energy estimation, analysis systematic uncertainties, including the implementation of systematics new to the NOvA analysis, and the Bayesian fit infrastructure using Markov Chain Monte Carlo (MCMC). The analysis yields the following credible intervals for the oscillation parameters assuming the normal ordering: δCP = 0.930+0.210 −0.290 π ∪0.150+0.150 −0.110 π, ∆m2 32 = 2.424+0.035 −0.040 × 10−3eV2, and sin2θ23 = 0.55+0.02 −0.06, with a 76% preference for normal ordering using a prior for sin2(2θ13) using Daya Bay’s measurement. If the Daya Bay sin2(2θ13) vs ∆m2 32 constraint is used as a prior instead, an 87% preference for normal ordering emerges.