Teenage depression has long been a significant yet underreported and therefore undertreated disease. In recent years depression-centric narratives like The Perks of Being a Wallflower, Dear Evan Hansen, and All the Bright Places have garnered both attention and controversy in print, film, and even Broadway, bringing the conversation around teenage mental health into the spotlight. While some of these depictions have been praised for promoting empathy and understanding, others have been criticized for including graphic or even sensationalized representations of teen depression and suicide. These depictions, fictional as they may be, contribute to the larger societal discourse on teen mental health. This paper examines one of the most influential works concerning adolescent mental health in recent years: Netflix’s Thirteen Reasons Why, with the aim of exploring how its status of both an “activist” work of art and a product affect its depiction of depression and anxiety — and how these depictions might affect a population that, in the wake of the pandemic, reports higher rates of depression and anxiety than ever.