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Scholarly Works (2 results)

Article
Peer Reviewed

Lack of associations of CHRNA5-A3-B4 genetic variants with smoking cessation treatment outcomes in Caucasian smokers despite associations with baseline smoking

Benowitz, Neal;
Tyndale, RF;
Zhu, AZX;
George, TP;
Paul, C;
Hawk, L;
Schnoll, R;
Swan, GE;
Benowitz, NL;
Heitjan, DF;
Lerman, C

UC San Francisco Previously Published Works (2015)

© 2015 Tyndale et al.CHRNA5-A3-B4 variants, rs16969968, rs588765 and rs578776, are consistently associated with tobacco consumption among smokers, but the association with smoking cessation is less consistent. Among the studies that reported significant as

Article
Peer Reviewed

Gender-stratified gene and gene-treatment interactions in smoking cessation

Benowitz, Neal;
Lee, W;
Bergen, AW;
Swan, GE;
Li, D;
Liu, J;
Thomas, P;
Tyndale, RF;
Benowitz, NL;
Lerman, C;
Conti, DV

UC San Francisco Previously Published Works (2012)

We conducted gender-stratified analyses on a systems-based candidate gene study of 53 regions involved in nicotinic response and the brain-reward pathway in two randomized clinical trials of smoking cessation treatments (placebo, bupropion, transdermal and