We consider the Directed Coulomb Explosion regime of ion acceleration from ultra-thin double layer (high Z/low Z) mass limited targets. In this regime the laser pulse evacuated the electrons from the irradiated spot and accelerates the remaining ion core in the direction of the laser pulse propagation. Then the moving ion core explodes due to the excess of positive charge forming a moving charge separation field that accelerates protons from the second layer. The utilization of the mass limited targets increases the effectiveness of the acceleration. It is also shown that different parameters of laser-target configuration should be chosen to ensure optimal acceleration by either linearly polarized or circularly polarized pulses.

Laser accelerated protons can be a complimentary source for treatment of oncological diseases to the existing hadron therapy facilities. We demonstrate how the protons, accelerated from near-critical density plasmas by laser pulses having relatively small power, reach energies which may be of interest for medical applications. When an intense laser pulse interacts with near-critical density plasma it makes a channel both in the electron and then in the ion density. The propagation of a laser pulse through such a self-generated channel is connected with the acceleration of electrons in the wake of a laser pulse and generation of strong moving electric and magnetic fields in the propagation channel. Upon exiting the plasma the magnetic field generates a quasi-static electric field that accelerates and collimates ions from a thin filament formed in the propagation channel. Two-dimensional Particle-in-Cell simulations show that a 100 TW laser pulse tightly focused on a near-critical density target is able to accelerate protons up to energy of 250 MeV. Scaling laws and optimal conditions for proton acceleration are established considering the energy depletion of the laser pulse.