China and Brazil are the world's leading exporter and importer of agrochemicals respectively. We combine quantitative and qualitative methods to analyze global-local interactions in the spatial restructuring of China's agrochemical industry in relation to a 2006 agrochemical import-acceleration policy in Brazil. We synthesize global political ecology and evolutionary economic geography (EEG) research on environmental regulations, technological upgrading, and the spatial transformations of China's pollution-intensive industries, discussing arguments that the Pollution Haven Hypothesis (PHH) and Porter Hypothesis (PH) co-exist due to firm heterogeneity. While existing studies conceptualize heterogeneity in terms of firm size, regional hub (cluster) effect, and local government intervention, this study adds global-local interactions as dimension of firm heterogeneity – distinguishing firms with weak and strong international linkages. We show the import-acceleration policy in Brazil contributed to the de-concentration of agrochemical production towards western China (confirming the PHH). Yet increasingly strict environmental regulations in China curtailed de-concentration after 2010, when well-established firms and new entrants with strong international linkages consolidated exports to Brazil, while new firms with weaker international linkages exited this market (confirming the PH). This co-existence of PHH and PH due to firm-level heterogeneity of global-local interactions illustrates a theoretical synthesis we call an evolutionary political economic geography (EPEG).