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Scholarly Works (1 results)

Article
Peer Reviewed

Strength of axial water ligation in substrate-free cytochrome P450s is isoform dependent

Ortiz De Montellano, Paul;
Conner, KP;
Schimpf, AM;
Cruce, AA;
McLean, KJ;
Munro, AW;
Frank, DJ;
Krzyaniak, MD;
Ortiz, P;
Bowman, MK;
Atkins, WM

UC San Francisco Previously Published Works (2014)

The heme-containing cytochrome P450s exhibit isoform-dependent ferric spin equilibria in the resting state and differential substrate-dependent spin equilibria. The basis for these differences is not well understood. Here, magnetic circular dichroism (MCD)