Background: Hypertension affects nearly one-third of adults globally, standing as a major cause of cardiovascular diseases such as stroke and heart attack (World Health Organization, 2021). Many patients rely on daily medications to control their hypertension. However, effective management is crucial, yet medication adherence remains a significant challenge, with non-adherence rates ranging from 7.1% to 66.2% (Márquez Contreras et al., 2019). In response to this challenge, various strategies have been developed and tested to improve medication compliance among hypertensive patients. These strategies include patient education, reminder systems, simplified medication regimens, and digital health interventions. Despite these efforts, achieving consistent adherence remains an ongoing struggle. Objective: The purpose of this review is to evaluate various interventions for managing hypertension in existing literature to determine the most effective strategy for improving medication compliance in adult patients.