A series of novel 8-amino BODIPY profluorescent nitroxides and the corresponding N-ethoxyamine derivatives were synthesized with varying substitution and molecular geometries. Single crystal X-ray diffraction data for the three 8-amino BODIPY nitroxides were obtained. UV-Vis absorption and emission data for the profluorescent nitroxides and 8-amino BODIPY N-ethoxyamine derivatives were examined to assess the utility of these compounds as fluorescent probes.