In a secularizing world, religious groups are increasingly threatened by anti-religious groups. We present two studies investigating religious peoples' responses to anti-religious threats. We expected intergroup threats to shape group-based emotions and behavioural intentions through a novel pathway whereby threat affects group-based meta-emotions: the ingroup's perception of the outgroup's emotions towards the ingroup. In Study 1, we experimentally manipulated threat and group salience with participants from two different cultures (British and Latinx/Hispanic). Study 1 demonstrated non-interactive effects of threat increasing negative emotional responses and of group salience strengthening emotional responses. The results illustrated the role of group-based meta-emotions in predicting outgroup-directed emotions and behavioural response intentions. Study 2 used a different manipulation of threat in an American sample and an identity-based manipulation of salience to assess the impact of real-world anti-religious campaigns involving symbolic and realistic threats. Both threat types increased negative group-based meta-emotions, negative outgroup-directed emotions, desire to respond, and opposition to the anti-religious campaign compared to no threat. Overall, religious identity salience had little impact on outcomes. The indirect pathway through meta-emotion replicated, suggesting the importance of considering this novel meta-emotion pathway in intergroup relations.