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The Relative Strength of Association of Ankle-Brachial vs. Toe-Brachial Index with Cardiovascular Mortality in Individuals With and Without Diabetes Mellitus.


Among diabetic individuals with clinically suspected PAD, both those with low and high ABI scores are at higher risk of CVD death. In contrast, a linear relationship was observed between TBI scores and CVD death irrespective of diabetes status. These findings suggest that stiffened ankle arteries may limit the predictive value of ABI scores in individuals with diabetes; a limitation that may be overcome by measurement of the TBI.

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