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Autism in the Balance: Elevated E-I Ratio as a Homeostatic Stabilization of Synaptic Drive
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https://doi.org/10.1016/j.neuron.2019.01.033Abstract
In this issue of Neuron, Antoine et al. (2019) find reduced feedforward inhibition in cortical neurons in four genetic mouse models of autism but without evidence of increased spontaneous or sensory-evoked activity.
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