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Sugar and spice: Fc glycosylation in antibody-mediated transplant rejection
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https://doi.org/10.1016/j.xcrm.2022.100809Abstract
Bharadwaj et al.1 demonstrate that anti-donor HLA antibodies display low levels of Fc fucosylation. This signature was associated with potent provocation of NK cell effector functions and was discriminative for active antibody-mediated rejection among patients with donor specific HLA antibodies.
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