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Open Access Publications from the University of California

Multiple eccrine spiradenomas in a zosteriform pattern

  • Author(s): Rosales Santillan, Monica
  • ATajnert, Kathrene
  • Swaby, Michael G
  • Migden, Michael R
  • Silapunt, Sirunya
  • et al.
Creative Commons 'BY-NC-ND' version 4.0 license

Eccrine spiradenoma (ES) typically presents as a solitary tender lesion. Multiple ES is a rare variant of ES and can present in a segmental, linear, blaschkoid, or zosteriform pattern. The etiology of multiple ES is unknown, but several theories have been suggested including a multipotent stem cell origin. We report the case of a 30-year-old woman with multiple painful ES in a zosteriform pattern on the mid-back and abdomen. Skin biopsy of a representative lesion demonstrated a circumscribed tumor nodule encapsulated by a fibrous capsule with diffuse dense basophilic proliferation located in the dermis. The lesions were then excised on two separate sessions without recurrence.

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