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Open Access Publications from the University of California

Imaging breast cancer chemotherapy response with light. Commentary on Soliman et al., p. 2605.

Creative Commons 'BY' version 4.0 license

Diffuse optical spectroscopy (DOS), which is used to image tumor metabolic response to neoadjuvant chemotherapy (NAC), shows large changes in tumor functional parameters with significant reductions in oxy- and deoxyhemoglobin for responders versus nonresponders. Although investigational, DOS may provide a cost-effective, risk-free method for optimizing NAC drug and dosing strategies for individual patients.

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