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Antigen-presenting nanoparticles for in vivo CAR T cell engineering
Published Web Location
https://doi.org/10.1038/s44222-026-00467-xAbstract
In vivo cell engineering enables chimeric antigen receptor (CAR) production directly within the body. Most in vivo CAR approaches target broad T cell populations. However, antigen-presenting nanoparticles could be used to engineer specific T cell subsets, leveraging the phenotypic and functional properties of the cells for T cell therapy.
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