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Microfluidic Cell Lysis Device for Point of Care Diagnostics

Abstract

Background

Point-of-care (POC) diagnostics provide quick results for patients in remote areas with limited access to laboratory equipment. Concurrently in-vitro diagnostic device market is a valued at $24 billion dollar and its expected to be valued at over $70 billion by 2020 • These diagnostics require access to intracellular components, such as DNA, which can be accessed by bursting open the cell, a process called cell lysis. Microfluidic technology allows for an entire laboratory procedure to miniaturized onto a small, portable platform, allowing for a quicker diagnostics and results.

 

Andrew Chavarin, Leovi Espitia, Saffi Khan, Marisa Lopez, Frederique Norpetlian, Abdullaah Tarif

Advisor: Professor William C. Tang

Mentor: Dr. Brad Sargent, Omnica Corporation, Irvine, CA

School of Engineering

Department of: Biomedical Engineering, Chemical and Material Science & Mechanical and Aerospace Engineering,

University of California-Irvine, CA

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