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Optimization of drug combinations using Feedback System Control
- Nowak-Sliwinska, Patrycja;
- Weiss, Andrea;
- Ding, Xianting;
- Dyson, Paul J;
- van den Bergh, Hubert;
- Griffioen, Arjan W;
- Ho, Chih-Ming
Published Web Location
https://doi.org/10.1038/nprot.2016.017Abstract
Nowak-Sliwinska et al. describe a protocol for optimizing drug combinations using Feedback System Control (FSC). Drug combinations are tested in a cell-based assay in which results are entered into the FSC pipeline to predict new combinations to be tested in vitro.
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