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Riboflavin: An Alternative Approach to Managing Migrane Attacks in the Adult Population

Abstract

Riboflavin may serve as a clinically important nutritional supplement in treating migraine attacks. But despite its potential therapeutic utility, riboflavin’s effects on patients with migraines have only been documented in four studies. Based on the results of these studies, comparing riboflavin with placebo demonstrated statistically significant improvements in many variables, among which included reduction of attack frequency, severity, and duration. However, these improvements were only noted in the adult population (Age > 18). Studies conducted on the pediatric population showed the opposite trend, with no statistically significant differences found between the placebo and riboflavin groups. Thus, riboflavin appears to have therapeutic value only when administered to adult patients suffering from migraine attacks.

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