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Metabolic repair through emergence of new pathways in Escherichia coli

2018
  • Pontrelli, Sammy;
  • Fricke, Riley C. B.;
  • Teoh, Shao Thing;
  • Lavina, Walter A;
  • Putri, Sastia Prama;
  • Fitz-Gibbon, Sorel;
  • Chung, Matthew;
  • Pellegrini, Matteo;
  • Fukusaki, Eiichiro;
  • Liao, James C.
et al.


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    • Fig. 1 β-alanine biosynthesis through uracil degradation.
    • Fig. 2 Characterization of mutations that contribute to the degradation of uracil into β-alanine.
    • Fig. 3 Emergence of β-alanine synthesis pathway using evolved ornithine decarboxylase.
    • Fig. 4 β-alanine pathway using SpeC and pathway reconstruction.
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