Skip to main content
Download PDF
- Main
Role of pancreatic cancer-derived exosomes in salivary biomarker development
- Author(s): Lau, C
- Kim, Y
- Chia, D
- Spielmann, N
- Eibl, G
- Elashoff, D
- Wei, F
- Lin, YL
- Moro, A
- Grogan, T
- Chiang, S
- Feinstein, E
- Schafer, C
- Farrell, J
- Wong, DTW
- et al.
Published Web Location
https://doi.org/10.1074/jbc.M113.452458Abstract
Background: Salivary biomarkers for systemic diseases have been undermined due to lack of mechanistic and biological rationale. Results: Suppression of exosome biogenesis leads to ablation of salivary biomarkers. Conclusion: Tumor-derived exosomes provide a mechanism for discriminatory biomarkers in saliva. Significance: Tumor-derived exosomes provide the scientific rationale that connects pancreatic tumors and the oral cavity leading to salivary biomarkers. © 2013 by The American Society for Biochemistry and Molecular Biology, Inc.
Many UC-authored scholarly publications are freely available on this site because of the UC's open access policies. Let us know how this access is important for you.