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Comparison of Depth of Sedation Performance between SedLine and BIS during General Anesthesia: Background and Protocol Development

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Abstract

The ideal end-tidal concentration of anesthetic dose for a patient under general anesthesia is dynamic and depends on factors. At present, no individual brain function monitoring device has been shown to be substantially superior. Prior studies have attempted to compare the performance of these devices, but a lack of space and common placement locations compromises interpretation. The aim of this protocol is to examine the concordance between processed EEG indices (BIS and PSI) and anesthesia provider assessments across a range of anesthetic depths using a custom engineered interface box.

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