Skip to main content
eScholarship
Open Access Publications from the University of California

Liver Imaging Reporting and Data System (LI-RADS) v2018: Impact on Categorization and Hepatocellular Carcinoma Staging.

  • Author(s): Chernyak, Victoria
  • Flusberg, Milana
  • Berman, Jesse
  • Fruitman, Kate C
  • Kobi, Mariya
  • Fowler, Kathryn J
  • Sirlin, Claude B
  • et al.

Published Web Location

https://aasldpubs.onlinelibrary.wiley.com/doi/epdf/10.1002/lt.25614
No data is associated with this publication.
Abstract

PURPOSE:To assess concordance in categorization and radiologic T staging using Liver Imaging Reporting and Data System (LI-RADS) v2017, LI-RADS v2018, and the Organ Procurement and Transplantation Network (OPTN) criteria. MATERIALS AND METHODS:All MR and CT reports using a standardized LI-RADS macro between 4/15-3/18 were identified retrospectively. Major features (size, arterial phase hyperenhancement [APHE], "washout,", enhancing "capsule", threshold growth) were extracted from the report for each LR-3, LR-4 and LR-5 observation. Each observation was assigned a new category based on LI-RADS v2017, v2018 and OPTN criteria. Radiologic T-stage was calculated based on size and number of LR-5 or OPTN-5 observations. Categories and T stages assigned by each system were compared descriptively. RESULTS:398 patients (67% male, mean age 63.4 years) with 641 observations (median size 14 mm) were included. 73/182 (40.1%) observations categorized LR-4 by LI-RADS v2017 were up-categorized to LR-5 by LI-RADS v2018 due to change in LR-5 criteria. 4/196 (2.0%) observations categorized LR-5 by LI-RADS v2017 were down-categorized to LR-4 by LI-RADS v2018 due to change in threshold growth definition. T stage was higher by LI-RADS v2018 than LI-RADS v2017 in 49/398 (12.3%) patients. Compared to OPTN stage, 12/398 (3.0%) patients were upstaged by LI-RADS v2017 and 60/398 (15.1%) by LI-RADS v2018. 5/101 (5.0%) patients with T2 stage based on LI-RADS v2017 and 10/102 (9.8%) patients with T2 stage based on LI-RADS v2018 did not meet T2 criteria based on OPTN criteria. Of the 98 patients with a T2 stage based on OPTN criteria, two (2.0%) had a stage T ≥ 3 based on LI-RADS v2017 and six (6.1%) had a stage T ≥ 3 based on LI-RADS v2018. CONCLUSION:LI-RADS v2018 increased the number of LR-5 observations by 40.1%, the radiologic T stage in 12.3% of patients, and overall discordance with OPTN T stage. This article is protected by copyright. All rights reserved.

Many UC-authored scholarly publications are freely available on this site because of the UC Academic Senate's Open Access Policy. Let us know how this access is important for you.

Item not freely available? Link broken?
Report a problem accessing this item