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Design of a hyperstable 60-subunit protein icosahedron
- Hsia, Yang;
- Bale, Jacob B;
- Gonen, Shane;
- Shi, Dan;
- Sheffler, William;
- Fong, Kimberly K;
- Nattermann, Una;
- Xu, Chunfu;
- Huang, Po-Ssu;
- Ravichandran, Rashmi;
- Yi, Sue;
- Davis, Trisha N;
- Gonen, Tamir;
- King, Neil P;
- Baker, David
Published Web Location
https://doi.org/10.1038/nature18010Abstract
The computational design of an extremely stable icosahedral self-assembling protein nanocage is presented; the icosahedron should be useful for applications ranging from calibrating fluorescence microscopy to drug delivery.
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