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Ceramide and sphingolipids are elevated across sample types in Crohn’s Disease compared to controls: A Systematic Review

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Abstract

Metabolomics refers to the analysis of patterns of small molecular metabolites in biological samples. Given the systemic effects of Crohn’s Disease (CD) on metabolite production, immune mediation, and microbiota growth, metabolomic studies undoubtedly provide clarity into disease course and prognosis. This is a comprehensive systematic review of human studies to identify common metabolite signatures in human CD.

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