UC San Diego

Biomolecular imaging is one of the rapidly developing areas of research in biomedical sciences. Since the discovery of Raman scattering by Raman and Krishnan and especially in the last few decades, significant progress has been made in developing Raman scattering-based imaging tools and their applications to studying biomolecules. Raman spectroscopy with enhancement and advances especially applied on lipid imaging is reviewed and discussed in the present study. Different Raman modalities and their performances are evaluated and compared in different aspects. Experimental performance of Raman imaging on lipid study is achieved with justified outcome. Raman spectroscopy could be justified as a powerful technique for biological imaging and lipid study.