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The role of the microenvironment in tumor immune surveillance
- Oluwadara, Oluwadayo;
- Giacomelli, Luca;
- Brant, Xenia;
- Christensen, Russell;
- Avezova, Raisa;
- Kossan, George;
- Chiappelli, Francesco
Published Web Location
https://doi.org/10.6026/97320630005285Abstract
The evidence appears compelling that the microenvironment, and associated biological cellular and molecular factors, may contribute to the progression of a variety of tumors. The effects of the microenvironment may directly influence the plasticity of T cell lineages, which was recently discussed (O'Shea & Paul, 2010 [4]). To review the putative role of the microenvironment in modulating the commitment of tumor immune surveillance, we use the model of oral premalignant lesions.
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