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Condensin-driven remodelling of X chromosome topology during dosage compensation
- Crane, Emily;
- Bian, Qian;
- McCord, Rachel Patton;
- Lajoie, Bryan R;
- Wheeler, Bayly S;
- Ralston, Edward J;
- Uzawa, Satoru;
- Dekker, Job;
- Meyer, Barbara J
Published Web Location
http://www.nature.com/nature/journal/v523/n7559/full/nature14450.htmlNo data is associated with this publication.
Abstract
Genome-wide chromosome conformation capture analysis in C. elegans reveals that the dosage compensation complex, a condensin complex, remodels the X chromosomes of hermaphrodites into a sex-specific topology distinct from autosomes while regulating gene expression chromosome-wide.
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